ArticleFrontiers in endocrinology2024
Association of stress hyperglycemia ratio with presence and severity of chronic kidney disease among US adults with diabetes mellitus.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Association between stress hyperglycemia ratio and cognitive function in older patients with diabetes or prediabetes: a cross-sectional study from the NHANES.Endocrine journal · 2026Article
- The Association Between Stress-Induced Hyperglycemia Ratio and Increased Urinary Albumin Excretion in Patients With Hypertension: A Population-Based Study.The Kaohsiung journal of medical sciences · 2026Article
- Stress hyperglycemia ratio and mortality risk in cardiometabolic multimorbidity: a multicenter retrospective study.BMC cardiovascular disorders · 2026Article
- Relative hyperglycemia and new-onset atrial fibrillation after coronary artery bypass grafting: a focus on stress hyperglycemia ratio.BMC cardiovascular disorders · 2025Article
- Association between stress hyperglycemia ratio and all-cause mortality in patients with acute kidney injury: a retrospective analysis of the MIMIC-IV database using machine learning.BMC nephrology · 2025Article
- Stress hyperglycemia ratio and the risk of new-onset chronic diseases: results of a national prospective longitudinal study.Cardiovascular diabetology · 2025Article
- Association between stress hyperglycemia ratio and neovascular glaucoma in patients with proliferative diabetic retinopathy.BMC ophthalmology · 2025Article
- Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database.BMC cardiovascular disorders · 2025Article
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- Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study.Frontiers in endocrinology · 2024Article
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7 authors.
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Abstract
Background: Among diabetes mellitus (DM) patients, stress hyperglycemia ratio (SHR) is a strong predictor of short- and long-term prognosis, and adverse cardiovascular events. However, whether SHR is associated with increased risk of presence and severity of chronic kidney (CKD) disease remains undetermined. Methods: Patients with DM from the National Health and Nutrition Examination Survey (NHANES) database (1999-2020) were included and divided into 5 groups according to their SHR level (quintile 1 to 5). Study outcomes were CKD, advanced CKD (ACKD), and CKD severity. Logistic regression and restricted cubic spline (RCS) were used to assess the association between the SHR and outcomes. Results: Totally, 6,119 patients were included. After adjustment, compared to patients with SHR in quintile 3 (as reference), the risk of CKD is 1.50 (P<0.001) for quintile 1, 1.23 (P=0.140) for quintile 2, 1.95 (P<0.001) for quintile 4, and 1.79 (P<0.001) for quintile 5. For the risk of ACKD, the OR is 1.46 (P=0.410) for quintile 1, 1.07 (P=0.890) for quintile 2, 3.28 (P=0.030) for quintile 4, and 3.89 (P=0.002) for quintile 5. For the CKD severity, the OR is 1.46 (P<0.001) for quintile 1, 1.20 (P=0.163) for quintile 2, 1.84 (P<0.001) for quintile 4, and 1.83 (P<0.001) for quintile 5. RCS analysis also showed a U-shaped association between SHR and outcomes (All P for nonlinearity<0.05). Conclusion: Our study demonstrated that too low or too high SHR level is significantly associated with adverse renal outcomes in patients with DM.
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