Evidence map›Paper›PMID 39502507›Full record

ArticleFEMS microbes2024

Contact with young children is a major risk factor for pneumococcal colonization in older adults.

Anne L Wyllie, Devyn Yolda-Carr, Maikel S Hislop, Sidiya Mbodj, Loren Wurst, Pari Waghela, Ronika Alexander-Parrish, Lindsay R Grant, Adriano Arguedas, Bradford D Gessner and 1 more

Abstract read
In one paragraph

Article in FEMS microbes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne L WyllieDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.ORCID https://orcid.org/0000-0001-6015-0279
Devyn Yolda-CarrDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.
Maikel S HislopDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.
Sidiya MbodjDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.
Loren WurstDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.
Pari WaghelaDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.
Ronika Alexander-ParrishPfizer Inc, Collegeville, PA 19426, United States.
Lindsay R GrantPfizer Inc, Collegeville, PA 19426, United States.ORCID https://orcid.org/0000-0002-4538-6424
Adriano ArguedasPfizer Inc, Collegeville, PA 19426, United States.
Bradford D GessnerPfizer Inc, Collegeville, PA 19426, United States.ORCID https://orcid.org/0000-0002-6216-7194
Daniel M WeinbergerDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Important questions remain about the sources of transmission of pneumococcus to older adults in the community. This is critical for understanding the potential effects of using pneumococcal conjugate vaccines (PCVs) in children and older adults. For non-institutionalized individuals, we hypothesized that the most likely source of adult-to-adult transmission is within the household. We designed a longitudinal study to sample adults ≥60 years of age living in the same household (New Haven, CT, USA), without younger residents in the household. Saliva samples and social and health questionnaires were obtained every 2 weeks for a period of 10 weeks. DNA extracted from culture-enriched saliva was tested using qPCR for pneumococcus genes

Indexed as

carriagepneumococcussalivasurveillancetransmission

Identifiers

PMID39502507
PMCPMC11536760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.