Evidence map›Paper›PMID 39502201›Full record

ArticleHeliyon2024

A case of unilateral focal choroidal excavation in Vogt-Koyanagi-Harada disease; case report.

Zhenbao Zhou, Liying Zhao, YuHuan Liu, Nan Zhuo, Han Chen, ShouBi Wang, YuYi Yang, LiBo Wang, XiangRu Zhou

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PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Zhenbao ZhouDepartment of Ophthalmology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Liying ZhaoDepartment of Ophthalmology, HongQi Hospital, MuDanJiang Medical University, China.
YuHuan LiuDepartment of Ophthalmology, HuiGuang Aier Eye Hospital, China.
Nan ZhuoDepartment of Ophthalmology, Traditional Chinese Medicine Hospital of Xiamen, China.
Han ChenDepartment of Ophthalmology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
ShouBi WangDepartment of Ophthalmology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
YuYi YangDepartment of Ophthalmology, HuiGuang Aier Eye Hospital, China.
LiBo WangDepartment of Ophthalmology, HuiGuang Aier Eye Hospital, China.
XiangRu ZhouDepartment of Ophthalmology, HongQi Hospital, MuDanJiang Medical University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report a rare case of Vogt-Koyanagi-Harada (VKH) disease complicated by unilateral focal choroidal excavation (FCE). Methods: A 25-year-old male patient with bilateral blurred vision, tinnitus, and headache. Initial examination revealed multiple sensory retinal detachments in both eyes. Optical coherence tomography (OCT), fundus fluorescein angiography (FFA), and other diagnostic tests confirmed VKH. The patient was treated with intravenous methylprednisolone followed by oral prednisolone. Results: Following treatment, the exudative retinal detachments resolved, and a subfoveal FCE was observed in the right eye. OCT imaging revealed choroidal inflammation and retinal pigment epithelium (RPE) disruption. The patient's visual acuity improved, but the FCE persisted during follow-up, suggesting a potential association between inflammation and the development of FCE in VKH. Conclusions: This case highlights the rare occurrence of FCE during the course of VKH disease, suggesting that inflammatory disruption of the RPE and choroidal atrophy may contribute to FCE formation. Comprehensive retinal imaging in VKH patients is essential for detecting such complications, which may influence long-term visual outcomes. This case adds to the limited literature on the relationship between ocular inflammation and choroidal excavation, providing valuable insights for future clinical management.

Indexed as

Case reportChoroidal inflammationFocal choroidal excavation (FCE)Vogt–Koyanagi–Harada (VKH)

Identifiers

PMID39502201
PMCPMC11535319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.