Evidence map›Paper›PMID 39501749›Full record

ReviewBioscience reports2024

Neuroprotective properties of zinc oxide nanoparticles: therapeutic implications for Parkinson's disease.

Kim San Tang, Wesley Zhi Chung See, Rakesh Naidu

Abstract readReview
In one paragraph

Review in Bioscience reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kim San TangSchool of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor, Malaysia.ORCID 0000-0003-2153-7184
Wesley Zhi Chung SeeJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor, Malaysia.
Rakesh NaiduJeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor, Malaysia.

Funding

Ministry of Higher Education, Malaysia (MOHE) FRGS/1/2020/SKK0/MUSM/03/5
6 · The paper itself

Abstract

Parkinson's disease (PD) significantly affects millions of people worldwide due to the progressive degeneration of dopamine-producing neurons in the substantia nigra pars compacta. Despite extensive research efforts, effective treatments that can halt or reverse the progression of PD remain elusive. In recent years, nanotechnology has emerged as a promising new avenue for addressing this challenge, with zinc oxide nanoparticles (ZnO-NPs) standing out for their extensive therapeutic potential. ZnO-NPs have shown remarkable promise in neuroprotection through several key mechanisms. The multifaceted properties of ZnO-NPs suggest that they could play a crucial role in intervening across various fundamental mechanisms implicated in PD. By targeting these mechanisms, ZnO-NPs offer new insights and potential strategies for managing and treating PD. This review aims to provide a thorough examination of the molecular mechanisms through which ZnO-NPs exert their neuroprotective effects. It highlights their potential as innovative therapeutic agents for PD and outlines directions for future research to explore and harness their full capabilities.

Indexed as

Neuroprotective AgentsParkinson DiseaseZinc OxideAnimalsHumansMetal NanoparticlesNanoparticlesNeuroprotective AgentsZinc Oxideamyloidapoptosisnanoparticlesoxidative stressParkinsons diseasezinc oxide

Identifiers

PMID39501749
PMCPMC11554912

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.