Evidence map›Paper›PMID 39501746›Full record

ArticleCytopathology : official journal of the British Society for Clinical Cytology2025

Navigating the Diagnostic Challenges in Lymph Node Cytology: The Case of Reactive Hyperplasia.

Elena Vigliar, Gennaro Acanfora, Mauro Buono, Claudio Bellevicine, Marco Picardi, Giancarlo Troncone

Abstract read
In one paragraph

Article in Cytopathology : official journal of the British Society for Clinical Cytology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elena VigliarDepartment of Public Health, University of Naples, "Federico II", Naples, Italy.ORCID 0000-0003-2856-9023
Gennaro AcanforaDepartment of Public Health, University of Naples, "Federico II", Naples, Italy.
Mauro BuonoUnit of Medical Physics and Radio Protection, A.O.U Policlinico Federico II, Naples, Italy.ORCID 0000-0003-1712-5849
Claudio BellevicineDepartment of Public Health, University of Naples, "Federico II", Naples, Italy.ORCID 0000-0002-7479-6457
Marco PicardiDepartment of Clinical Medicine and Surgery, University of Naples, "Federic II", Naples, Italy.
Giancarlo TronconeDepartment of Public Health, University of Naples, "Federico II", Naples, Italy.ORCID 0000-0003-1630-5805

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fine needle cytology (FNC) is a pivotal diagnostic tool for distinguishing between benign and malignant lymphadenopathies mainly because of its minimal invasiveness, cost-effectiveness and accuracy. A major requirement for maximising diagnostic accuracy is proper sample management of aspirated cellular material. In this diagnostic process, the morphological evaluation of adequate smears is paramount, guiding cytopathologists in the selection of appropriate ancillary tests through the recognition of cell size and patterns of distribution. Here, we describe a peculiar 'concentric ovals distribution pattern', frequently observed in the FNC of benign reactive lymph nodes, which may represent an aid in the cytological diagnosis of reactive hyperplasia.

Indexed as

CytodiagnosisHyperplasiaLymph NodesAdultBiopsy, Fine-NeedleDiagnosis, DifferentialFemaleHumansMale

Identifiers

PMID39501746
PMCPMC11632165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.