Evidence map›Paper›PMID 39501403›Full record

ArticleAIDS research and therapy2024

AIDS mortality in Brazil, 2012-2022: a time series study.

Lucas de Souza Luna, Rafael Pedro de Souza Nascimento, Paula Esbaltar de Oliveira, Adeilton Gonçalves da Silva Junior, Márcio Bezerra-Santos, Rodrigo José Videres Cordeiro de Brito, Rodrigo Feliciano do Carmo, Carlos Dornels Freire de Souza

Abstract read
In one paragraph

Article in AIDS research and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucas de Souza LunaFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Rafael Pedro de Souza NascimentoFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Paula Esbaltar de OliveiraFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Adeilton Gonçalves da Silva JuniorFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Márcio Bezerra-SantosFederal University of Alagoas (UFAL), Arapiraca, Alagoas, Brazil.
Rodrigo José Videres Cordeiro de BritoFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Rodrigo Feliciano do CarmoFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil.
Carlos Dornels Freire de SouzaFederal University of the São Francisco Valley (UNIVASF), Av José Maniçoba, s/n, Centro, Petrolina, Pernambuco, 56.304-205, Brazil. carlos.dornels@univasf.edu.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman immunodeficiency virus (HIV) infection is a health problem in Brazil and worldwide. Without treatment, the infection can progress to Acquired Immunodeficiency Syndrome (AIDS), with a high mortality potential. The objective of this study was to analyze the time trend of AIDS mortality in Brazil, macro-regions, federal units and their respective capitals, from 2012 to 2022.

methodsThis is a time-series study of all AIDS deaths in Brazil from 2012 to 2022. The study included the annual number of deaths and the crude and standardized mortality rates. The Joinpoint regression model was used for the time analysis of the standardized rates. Annual percentage change (APC) and average annual percentage change (AAPC) were calculated. A 95% confidence interval (CI) and a 5% significance level were used.

resultsDuring the period analyzed, 128,678 AIDS deaths were recorded in Brazil, with a crude mortality rate of 6.3/100,000 and a standardized mortality rate of 5.3/100,000. From 2012 to 2020, three regions showed a declining trend in AIDS mortality: Central-West (AAPC - 2.3%; 95%CI -4.3 to -0.21; p = 0.03), Southeast (AAPC - 5.6%; 95%CI -6.8 to -4.0; p < 0.001), and South (AAPC - 4.4%; 95%CI -5.27 to -3.6; p < 0.001). There was also a downward trend in 10 states and 10 capitals. There was an increase in the number of deaths from 2020 onwards in the North, Northeast and Southeast regions compared to 2019.

conclusionThere was a downward trend in AIDS mortality from 2012 to 2020 and an upward trend from 2020 to 2022. The regional differences observed could reflect the social disparities that exist in Brazil. In addition, the Covid-19 pandemic has had an impact on the process of dealing with HIV in Brazil.

Indexed as

Acquired Immunodeficiency SyndromeAdultBrazilFemaleHIV InfectionsHumansMaleMiddle AgedMortality

Identifiers

PMID39501403
PMCPMC11536946

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.