ArticleBMC pulmonary medicine2024
Association between prognostic nutritional index and mortality risk in patients with community-acquired pneumonia: a retrospective study.
Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of the prognostic nutritional index in sepsis, pneumonia, and tuberculosis: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Clinical outcomes and prognostic factors of open-window thoracostomy for empyema: a retrospective review of 40 patients.Surgery today · 2026Article
- Predictive value of the prognostic nutritional index and aggregate index of systemic inflammation for pulmonary complications in children with influenza.Translational pediatrics · 2026Article
- Association between prognostic nutritional index and clinical outcomes in patients with pyogenic liver abscess: a retrospective multicenter study.BMC infectious diseases · 2026Article
- Clinical Predictors of Worsening in Non-severe Acute Cholangitis.Internal medicine (Tokyo, Japan) · 2026Article
- Prognostic value of cardiac troponin I in hospitalized patients with community-acquired pneumonia: A retrospective cohort study.Medicine · 2026Article
- Stroke-Associated Pneumonia and Impaired Functional Recovery After Stroke: The Role of Nutritional-Inflammatory Factors.Advances in respiratory medicine · 2026Article
- Association between albumin-based nutritional inflammation indices and all-cause mortality in patients with severe pneumonia.BMC infectious diseases · 2026Article
- Prognostic Value of the National Early Warning Score Combined with Nutritional and Endothelial Stress Indices for Mortality Prediction in Critically Ill Patients with Pneumonia.Medicina (Kaunas, Lithuania) · 2026Article
- Contribution of pectoralis muscle index to mortality prediction in older adults with community-acquired pneumonia.Medicine · 2026Observational
- Development and validation of a nomogram integrating inflammatory-nutritional-metabolic composite indices for predicting short-term adverse outcomes in hospitalized patients with pneumonia.Frontiers in medicine · 2026Article
- Risk factors for malnutrition and its impact on prognosis in patients with severe pneumonia.Frontiers in nutrition · 2026Article
- Association between prognostic nutritional index and 90-day readmission in patients with acute exacerbation of chronic obstructive pulmonary disease: a multicenter study.Frontiers in nutrition · 2026Article
- Article
- Evaluating pre-transplant nutritional indices as predictors of pneumonia and mortality in multiple myeloma patients post-autologous stem cell transplantation.BMC pulmonary medicine · 2025Article
- Association between the geriatric nutritional risk index and all-cause mortality in older critically ill patients with community-acquired pneumonia.Nutrition journal · 2025Article
- Association between the nutritional inflammation index and mortality among patients with sepsis: insights from traditional methods and machine learning-based mortality prediction.BMC infectious diseases · 2025Article
- Association between prognostic nutritional index and all-cause mortality in critically ill patients with ventilator-associated pneumonia: a retrospective study based on MIMIC-IV database.Frontiers in nutrition · 2025Article
- Preoperative prognostic nutritional index as a predictive factor for postoperative pneumonia in esophageal cancer patients undergoing esophagectomy.Frontiers in nutrition · 2025Article
- Association between prognostic nutritional index and all-cause mortality among intestinal obstruction patients in the intensive care unit: a retrospective study.Frontiers in nutrition · 2025Article
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Abstract
backgroundThe prognostic nutritional index (PNI), reflecting the body's immune-nutritional status, has been established as a correlate of prognosis across various diseases. However, its significance in community-acquired pneumonia (CAP) remains unclear. This study investigated the relationship between PNI and clinical outcomes in CAP patients.
methodsIn this retrospective cohort study, we aimed to evaluate the prognostic value of the PNI in adults with CAP admitted to the ICU. Participants were selected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and categorized into quartiles (Q1-Q4) according to their PNI values. We employed Kaplan-Meier survival analysis, multivariate Cox regression, and restricted cubic spline (RCS) models to explore the association between PNI and the clinical outcomes of these CAP patients.
resultsIn this study, we included 1,608 patients with CAP. The observed 30-day and 90-day mortality rates stood at 30.85% and 39.99%, respectively. Patients with higher PNI levels exhibited a reduced risk of both 30-day and 90-day mortality. Following adjustment for confounders, PNI showed a significant negative association with 30-day mortality [HR, 0.93 (0.91-0.94), P < 0.001] and 90-day mortality [HR, 0.94 (0.92-0.95), P < 0.001]. RCS analysis revealed a consistent trend of declining all-cause mortality risk corresponding to increasing PNI values. PNI demonstrated predictive value for 30-day and 90-day mortality in CAP patients, with AUCs of 0.71 and 0.68, respectively. Combining PNI with CURB-65 enhanced the predictive value of CURB-65.
conclusionOur investigation identified a significant negative association between the PNI and the risk of mortality in patients with CAP. Additionally, the PNI demonstrated superior predictive value for mortality risk in CAP patients when compared to the CURB-65 scoring system.
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