Evidence map›Paper›PMID 39501181›Full record

ArticleBMC ophthalmology2024

Assessment of potential myopia risk factors, including chronotype, in Estonian adolescents: a cross-sectional study.

Teele Palumaa, Delis Linntam, Reili Rebane, Kristel Harak, Mari Tamsalu, Katrin Sõnajalg, Karina Ülper, Svetlana Belova, Triin Keller, Marika Tammaru and 1 more

Abstract read
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The application of artificial intelligence in myopia prediction for children and adolescents: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Circadian rhythms regulate refractive development across species.bioRxiv : the preprint server for biology · 2026
    Article
  4. IMI-2025 Digest.Investigative ophthalmology & visual science · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Teele PalumaaEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia. teele@palumaa.uk.
Delis LinntamEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Reili RebaneEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Kristel HarakEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Mari TamsaluEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Katrin SõnajalgEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Karina ÜlperEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Svetlana BelovaEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Triin KellerEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.
Marika TammaruResearch Department, East Tallinn Central Hospital, Tallinn, Estonia.
Kadi PalumaaEye Clinic, East Tallinn Central Hospital, Ravi 18, Tallinn, 10138, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyopia is a growing healthcare concern worldwide. Increasing evidence suggests that sleep and circadian rhythms may be associated with myopia. Furthermore, the risk factors of myopia have not been studied in the Estonian population to date. This study aimed to evaluate chronotype, lifestyle factors, and parental myopia in relation to myopia in Estonian secondary school students.

methodsGrade 10 students from three secondary schools in Tallinn, each with distinct focuses: one science-oriented, one arts-oriented, and one sports-oriented, were invited to participate. They underwent a comprehensive ocular examination, including cycloplegic autorefraction and ocular biometry. Chronotype was evaluated with the Morningness - Eveningness Questionnaire. Participants reported parental myopia and replied to a set of questions, separately for schooldays and free days, to indicate the amount of time they spent outdoors, doing near work and intermediate distance activities. Myopia was defined as cycloplegic SER ≤ - 0.50 D. Logistic regression analysis was performed to assess the association of the studied factors with myopia.

resultsA total of 123 students (57% female) participated in the study, with a mean age of 16.71 years (standard deviation 0.41). In a multivariable regression model, having two myopic parents was associated with higher odds of myopia (OR 3.78, 95% CI 1.15 - 12.42). We found no association between myopia and chronotype. Notably, time spent outdoors and doing near work or intermediate distance work did not affect the likelihood of having myopia. We observed that students attending the sports-oriented school had lower odds of myopia than those attending the science-oriented school (OR 0.12, 95% CI 0.03-0.51).

conclusionChronotype was not associated with myopia in our study sample. Consistent with previous reports, we identified parental myopia as a myopia risk factor. Interestingly, there was no association between myopia and time spent outdoors or near work. However, the odds of myopia varied depending on the school attended by the participants, which may reflect the educational load or lifestyle of participants in earlier childhood.

Indexed as

Circadian RhythmMyopiaAdolescentChronotypeCross-Sectional StudiesEstoniaFemaleHumansLife StyleMaleParentsRefraction, OcularRisk FactorsSleepStudentsSurveys and QuestionnairesChronotypeCircadian rhythmsMyopiaRisk factors

Identifiers

PMID39501181
PMCPMC11539277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.