Evidence map›Paper›PMID 39500999›Full record

ArticleScientific reports2024

Osteocalcin and Chinese visceral adiposity index are associated with the risk of ASCVD and arterial stiffness in patients with T2DM.

Caixia Gong, Chongyang Chen, Yangting Zhao, Yawen Wang, Kai Li, Xiaoyu Lv, Jie Gao, Pingping Zhao, Songbo Fu, Jingfang Liu

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Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Caixia GongThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Chongyang ChenThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Yangting ZhaoThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Yawen WangThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Kai LiThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Xiaoyu LvThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Jie GaoThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Pingping ZhaoThe First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China.
Songbo FuDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Jingfang LiuDepartment of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China. ljf824168@126.com.

Funding

Health industry scientific research project of Gansu Province No. GSWSKY-2019-07National Natural Science Foundation of China No.82360161, No.81960155The Hospital Fund of the First Hospital of Lanzhou University ldyyyn2020-01
6 · The paper itself

Abstract

This study aims to discover the association between serum osteocalcin, the Chinese visceral adiposity index (CVAI), and atherosclerotic cardiovascular disease (ASCVD) risk, and their impact on arterial stiffness in T2DM patients. We included 639 T2DM patients aged 30 and older who received the assessment of ASCVD risk using the China-PAR equation, Osteocalcin and arterial stiffness in this cross-sectional study. We found that osteocalcin and CVAI as independent risk factors for both medium-high-risk ASCVD (osteocalcin: men, OR,0.96, 95% CI 0.92, 1.00; women, OR, 0.93, 95% CI 0.8, 1.08, respectively)(CVAI: men, OR,1.01,95% CI 1.00,1.02; women: OR, 1.08, 95% CI 1.02,1.14, respectively) and arterial stiffness (osteocalcin: men, OR, 0.98, 95% CI 0.94,1.01; women, OR, 0.98, 95% CI 0.90,1.06, respectively)(CVAI: men, OR,1.0, 95% CI 0.99,1.01; women, OR, 1.02, 95% CI 1.00,1.04, respectively) in both men and women patients with T2DM. Combining osteocalcin levels and CVAI improved the prediction accuracy of arterial stiffness in men patients with T2DM (difference of AUC

Indexed as

AtherosclerosisDiabetes Mellitus, Type 2OsteocalcinVascular StiffnessAdiposityAdultAgedChinaCross-Sectional StudiesEast Asian PeopleFemaleHumansIntra-Abdominal FatMaleMiddle AgedObesity, AbdominalOsteocalcinArterial stiffnessAtherosclerosisAtherosclerotic cardiovascular disease riskChina visceral fat indexOsteocalcin

Identifiers

PMID39500999
PMCPMC11538503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.