Evidence map›Paper›PMID 39500978›Full record

ArticleScientific reports2024

An all-atom model of the human cardiac sodium channel in a lipid bilayer.

Garrett M Knotts, Spencer K Lile, Emily M Campbell, Taylor A Agee, Senal D Liyanage, Steven R Gwaltney, Christopher N Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Garrett M Knotts *Department of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Spencer K Lile *Department of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Emily M CampbellDepartment of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Taylor A AgeeDepartment of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Senal D LiyanageDepartment of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Steven R GwaltneyDepartment of Chemistry, Mississippi State University, Starkville, MS, 39759, USA.
Christopher N JohnsonDepartment of Chemistry, Mississippi State University, Starkville, MS, 39759, USA. cn.johnson@chemistry.msstate.edu.

Funding

Calcium modification of voltage gated sodium channelsR35GM142868 · NIGMS · MISSISSIPPI STATE UNIVERSITY · PI JOHNSON, CHRISTOPHER N. · 2021 to 2025
$2.0M
NIGMS NIH HHS R35 GM142868
6 · The paper itself

Abstract

Voltage-gated sodium channels (Na

Indexed as

Lipid BilayersNAV1.5 Voltage-Gated Sodium ChannelCryoelectron MicroscopyHumansModels, MolecularMolecular Dynamics SimulationProtein ConformationLipid BilayersNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, humanActivation gateC-terminal domain interactionInactivation gateLatch-receptor interactionVoltage-gated sodium channels

Identifiers

PMID39500978
PMCPMC11538489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.