ArticleNature communications2024
An ultrasensitive multimodal intracranial pressure biotelemetric system enabled by exceptional point and iontronics.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Intratumoral therapeutic dust for chemo-photodynamic combination treatment.Science advances · 2026Article
- A highly sensitive and drift-free iontronic sensor enabled by a polarity-balanced polyelectrolyte for surgical force sensing.Science advances · 2026Article
- Clarifying the landscape of mechanical sensors from stress to strain.Nature sensors · 2026Article
- Exceptional point-enhanced piezoelectric thermometry via anti-parity-time symmetry.Microsystems & nanoengineering · 2026Article
- Critical point-based wireless sensors enabling tiny perturbation detection.Science advances · 2026Article
- Laser-fabricated reconfigurable PT-symmetric sensors for wireless health monitoring of CFRP structures.Microsystems & nanoengineering · 2026Article
- Noise-resilient exceptional point sensing with immunity to undesired perturbations.Science advances · 2026Article
- Wireless battery-free ultrathin lithium-niobate resonator as wearable and implantable electronics for continuous monitoring of mechanical vital signs.Nature communications · 2025Article
- NFC/RFID-enabled wearables and implants for biomedical applications.Microsystems & nanoengineering · 2025Review
- Ultra-Sensitive Wireless Capacitive Nanocomposite-Based Pressure Sensors for Health Monitoring.Advanced materials technologies · 2025Article
- The Collapse of Brain Clearance: Glymphatic-Venous Failure, Aquaporin-4 Breakdown, and AI-Empowered Precision Neurotherapeutics in Intracranial Hypertension.International journal of molecular sciences · 2025Review
- Recent Advances in Flexible Sensors for Neural Interfaces: Multimodal Sensing, Signal Integration, and Closed-Loop Feedback.Biosensors · 2025Review
- Advanced Morphological and Material Engineering for High-Performance Interfacial Iontronic Pressure Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
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Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The accurate monitoring of vital physiological parameters, exemplified by heart rate, respiratory rate, and intracranial pressure (ICP), is of paramount importance, particularly for managing severe cranial injuries. Despite the rapid development of implantable ICP sensing systems over the past decades, they still suffer from, for example, wire connection, low sensitivity, poor resolution, and the inability to monitor multiple variables simultaneously. Here, we propose an ultrasensitive multimodal biotelemetric system that amalgamates an iontronic pressure transducer with exceptional point (EP) operation for the monitoring of ICP signals. The proposed system can exhibit extraordinary performance regarding the detection of minuscule ICP fluctuation, demonstrated by the sensitivity of 115.95 kHz/mmHg and the sensing resolution down to 0.003 mmHg. Our system excels not only in the accurate quantification of ICP levels but also in distinguishing respiration and cardiac activities from ICP signals, thereby achieving the multimodal monitoring of ICP, respiratory, and heart rates within a single system. Our work may provide a pragmatic avenue for the real-time wireless monitoring of ICP and thus hold great potential to be extended to the monitoring of other vital physiological indicators.
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