Evidence map›Paper›PMID 39500849›Full record

Trial reportReproductive sciences (Thousand Oaks, Calif.)2024

Comparison of Letrozole Versus Combination Letrozole and Clomiphene Citrate (CC) for Ovulation Induction in Sub Fertile Women with Polycystic Ovarian Syndrome (PCOS)-An Open Label Randomized Control Trial.

Sharmistha Sarkar, Nivedita Gupta, Treasa Joseph, Bijesh Yadav, Aleyamma T Kunjummen, Mohan S Kamath

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Reproductive sciences (Thousand Oaks, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sharmistha SarkarDepartment of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004.
Nivedita GuptaDepartment of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004.
Treasa JosephDepartment of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004.ORCID 0000-0002-1952-9364
Bijesh YadavDepartment of Biostatistics, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004.
Aleyamma T KunjummenDepartment of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004. draleyammatk@hotmail.com.ORCID 0000-0001-6506-0133
Mohan S KamathDepartment of Reproductive Medicine and Surgery, Christian Medical College Hospital, Vellore, Tamil Nadu, India, 632004.ORCID 0000-0002-0316-636X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effectiveness of Letrozole and Clomiphene (CC) combination versus Letrozole alone for ovulation induction in infertile women with PCOS. This was an open label randomized controlled trial conducted between September 2020 and March 2023 at a tertiary level hospital. Women with a diagnosis of infertility and PCOS were included. Participants were randomized in a 1:1 ratio, to either the combination of 2.5 mg letrozole and 50 mg Clomiphene Citrate (CC) daily or 2.5 mg letrozole alone from 2nd to 6

Indexed as

ClomipheneDrug Therapy, CombinationFertility Agents, FemaleInfertility, FemaleLetrozoleOvulation InductionPolycystic Ovary SyndromePregnancy RateAdultAromatase InhibitorsFemaleHumansOvulationPregnancyTreatment OutcomeYoung AdultAromatase InhibitorsClomipheneFertility Agents, FemaleLetrozoleClomiphene citrateLetrozoleOvulation inductionPolycystic ovary syndromeSubfertility

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.