Evidence map›Paper›PMID 39500570›Full record

ArticleNMR in biomedicine2025

Dynamic glucose-enhanced MRI of gliomas: A preliminary clinical application.

Jianhua Mo, Xiang Xu, Andong Ma, Mingjun Lu, Xianlong Wang, Qihong Rui, Jianbin Zhu, Haitao Wen, Genyun Lin, Linda Knutsson and 2 more

Abstract read
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Dynamic glucose-enhanced MRI in brain tumors.Magma (New York, N.Y.) · 2026
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jianhua MoDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiang XuIcahn School of Medicine at Mount Sinai, BioMedical Engineering and Imaging Institute, New York, New York, USA.
Andong MaDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Mingjun LuDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xianlong WangDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Qihong RuiDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jianbin ZhuDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Haitao WenDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Genyun LinDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Linda KnutssonDepartment of Medical Radiation Physics, Lund University, Lund, Sweden.ORCID 0000-0002-4263-113X
Peter van ZijlRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Zhibo WenDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Funding

Development and Translation of D-glucose as a Diagnostic Agent for MRI of CancerR01EB019934 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2015 to 2019
$5.7M
Development and Translation of D-glucose as an MRI Contrast Agent for Multiple SclerosisR00EB026312 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI XU, XIANG · 2020 to 2022
$747k
Natural Science Fundation of Guangdong Province 2022A1515011585NIBIB NIH HHS R00 EB026312NIBIB NIH HHS R01 EB019934NIH HHS R00EB026312NIH HHS R01EB019934Southern Medical University Clinical Research Project LC2016ZD028Swedish Brain Foundation FO2021-0328Swedish Cancer Society 21 1652PjSwedish Cancer Society CAN 2018/550Swedish Research Council 2019-03637The Scientific Research Funding Project of the Nanfang Medical Imaging Alliance FS202301008
6 · The paper itself

Abstract

The study aimed to investigate the feasibility of dynamic glucose-enhanced (DGE) MRI technology in the clinical application of glioma. Twenty patients with glioma were examined using a preoperative DGE-MRI protocol before clinical intervention. A brief hyperglycemic state was achieved by injecting 50 mL of 50% w/w D-glucose intravenously during the DGE imaging. The total acquisition time for the DGE was 15 min. Area-under-the-curve (AUC) images were calculated using the DGE images. AUC

Indexed as

Brain NeoplasmsGliomaGlucoseMagnetic Resonance ImagingAdultAgedArea Under CurveFemaleHumansMaleMiddle AgedGlucosedynamic enhancedgliomaglucoseglucoseCESTMRI

Identifiers

PMID39500570
PMCPMC11604297

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.