Evidence map›Paper›PMID 39500378›Full record

ArticleProceedings. Biological sciences2024

Resistance to age-related hearing loss in the echolocating big brown bat (

Grace Capshaw, Clarice A Diebold, Danielle M Adams, Jack G Rayner, Gerald S Wilkinson, Cynthia F Moss, Amanda M Lauer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings. Biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A tale of two ears: development of binaural auditory processing in the big brown bat.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Grace CapshawDepartment of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0002-5688-2538
Clarice A DieboldDepartment of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0003-3678-3003
Danielle M AdamsDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0002-8260-4064
Jack G RaynerDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0001-9259-9046
Gerald S WilkinsonDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0001-7799-8444
Cynthia F MossDepartment of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0001-6916-0000
Amanda M LauerThe Solomon H. Snyder Dept of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.ORCID 0000-0003-4184-7374

Funding

Training Program in Hearing and BalanceT32DC000023 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CULLEN, KATHLEEN E · 1989 to 2025
$8.7M
Social stress, epigenetics and immune function across bat lifespansR33AG078474 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI GERALD S WILKINSON · 2024 to 2026
$1.6M
Optical tools to probe neural circuits in the echolocating batR34NS118462 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KUCHIBHOTLA, KISHORE V, WOHLGEMUTH, MELVILLE J · 2020 to 2020
$705k
Social stress, epigenetics and immune function across bat lifespansR61AG078474 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI WILKINSON, GERALD S · 2022 to 2023
$601k
David M. Rubenstein Fund for Hearing ResearchNational Science FoundationNIA NIH HHS R33 AG078474NIA NIH HHS R61 AG078474NIDCD NIH HHS T32 DC000023NINDS NIH HHS R34 NS118462NINDS NIH HHS R34 NS118462-01NSF Division of Biological Infrastructure DBI-2213824Office of Naval ResearchOffice of Naval Research N00014-22-1-2793
6 · The paper itself

Abstract

Hearing mediates many behaviours critical for survival in echolocating bats, including foraging and navigation. Although most mammals are susceptible to progressive age-related hearing loss, the evolution of biosonar, which requires the ability to hear low-intensity echoes from outgoing sonar signals, may have selected against the development of hearing deficits in bats. Many echolocating bats exhibit exceptional longevity and rely on acoustic behaviours for survival to old age; however, relatively little is known about the ageing bat auditory system. In this study, we used DNA methylation to estimate the ages of wild-caught big brown bats (

Indexed as

AgingChiropteraEcholocationEvoked Potentials, Auditory, Brain StemHearing LossAnimalsCochleaDNA MethylationFemaleHearingMaleauditory ageingChiropteracochleapresbycusis

Identifiers

PMID39500378
PMCPMC11708781

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.