Evidence map›Paper›PMID 39500005›Full record

ArticleAmerican journal of surgery2025

Demystifying delays: Factors associated with timely treatment of adrenocortical carcinoma.

Jesse E Passman, Julia A Gasior, Sara P Ginzberg, Wajid Amjad, Amanda Bader, Jasmine Hwang, Heather Wachtel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jesse E PassmanDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA. Electronic address: Jesse.Passman@pennmedicine.upenn.edu.
Julia A GasiorDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Sara P GinzbergDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA.
Wajid AmjadDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA.
Amanda BaderDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA.
Jasmine HwangDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA.
Heather WachtelDepartment of Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

A genotype-phenotype study of germline succinate dehydrogenase pathogenic variantsK08CA270385 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Heather Wachtel · 2022 to 2026
$967k
NCI NIH HHS K08 CA270385
6 · The paper itself

Abstract

backgroundDelays in management of adrenocortical carcinoma (ACC) may lead to worse outcomes. We assessed for delays in ACC treatment according to sociodemographic factors.

methodsWe performed a retrospective cohort study of patients treated for ACC (2010-2019) utilizing the National Cancer Database. Cox proportional hazards modeling was used to evaluate the associations between sociodemographic, geographic, and clinical factors and time to intervention from diagnosis.

resultsAcross 1399 subjects treated for ACC, the median time to treatment was 27 days (IQR 15-47). Non-Hispanic Black patients (HR 0.798, p ​= ​0.033) and patients aged 40-64 years (HR 0.800, p ​= ​0.008) were at greater risk of delays in care, whereas female patients (HR 1.169, p ​= ​0.011) and those with metastatic disease (HR 1.176, p ​= ​0.010) received more timely care.

conclusionsOlder age, male sex, and Black race were associated with delays in care for ACC though these delays did not translate to worsened overall survival.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaTime-to-TreatmentAdultAgedAge FactorsFemaleHumansMaleMiddle AgedRetrospective StudiesSex FactorsUnited StatesACCAdrenalAdrenocortical carcinomaDelays in careDisparitiesEndocrineOutcomes

Identifiers

PMID39500005
PMCPMC13215123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.