Evidence map›Paper›PMID 39499865›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Increased Bone Morphogenetic Protein-Responsive Transcription Factors in Distinct Endothelial and Mesenchymal Cells in Pulmonary Artery Hypertension.

Adam Michael Andruska, Rodrigo Cantu Valadez, Kenzo Ichimura, Pauline Chu, Tianyi Zhang, Katharina Schimmel, Lingli Wang, Aiqin Cao, Micheala A Aldred, Edda Spiekerkoetter

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adam Michael AndruskaDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0001-5238-2344
Rodrigo Cantu ValadezDepartment of Physics, University of California, Berkeley, California; and.
Kenzo IchimuraDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0002-5734-335X
Pauline ChuDepartment of Pathology, and.
Tianyi ZhangDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.
Katharina SchimmelDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0001-7002-5113
Lingli WangDivision of Cardiology, Department of Pediatrics, Stanford University, Stanford, California.
Aiqin CaoDivision of Cardiology, Department of Pediatrics, Stanford University, Stanford, California.
Micheala A AldredDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana.ORCID 0000-0002-7390-9181
Edda SpiekerkoetterDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine.ORCID 0000-0002-3868-5186

Funding

Pulmonary Hypertension Breakthrough InitiativeR24HL123767 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ALDRED, MICHEALA A, ERZURUM, SERPIL C. · 2014 to 2017
$10.1M
Understanding and targeting molecular and cellular events responsible for pulmonary arteriovenous malformation development, growth and regressionR01HL169787 · NHLBI · STANFORD UNIVERSITY · PI Edda Frauke Spiekerkoetter · 2023 to 2026
$2.8M
Defining the cellular and molecular mechanisms driving neointimal lesion growth in pulmonary hypertensionR01HL163013 · NHLBI · STANFORD UNIVERSITY · PI KUMAR, MAYA ELISE · 2022 to 2025
$2.7M
Targeting Novel BMPR2 modifiers in Pulmonary Hypertension with Repurposed DrugsR01HL128734 · NHLBI · STANFORD UNIVERSITY · PI SPIEKERKOETTER, EDDA FRAUKE · 2016 to 2020
$2.1M
What triggers RV Fiber Re-Orientation in response to RV pressure overload, and what is its Consequence on Inter-Ventricular Decoupling?R01HL152250 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Vitaly Kheyfets · 2023 to 2026
$1.9M
Understanding and targeting molecular as well as structural events governing right ventricular adaptation, failure and recovery in pulmonary hypertension using repurposed drugsR01HL158868 · NHLBI · STANFORD UNIVERSITY · PI SPIEKERKOETTER, EDDA FRAUKE · 2021 to 2024
$1.7M
Francis Family Foundation Parker B Francis FellowshipNHLBI NIH HHS R01 HL128734NHLBI NIH HHS R01 HL152250NHLBI NIH HHS R01 HL158868NHLBI NIH HHS R01 HL163013NHLBI NIH HHS R01 HL169787NHLBI NIH HHS R24 HL123767NHLBI NIH HHS Tissue samples were provided by the Pulmonary HypeNIH HHS R01HL152250NIH HHS R01HL158868NIH HHS R01HL163013NIH HHS R01HL169787
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39499865
PMCPMC11755370

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.