Evidence map›Paper›PMID 39499805›Full record

Trial reportAnnals of the American Thoracic Society2025

Bexotegrast Shows Dose-Dependent Integrin α

Joshua J Mooney, Susan Jacobs, Éric A Lefebvre, Gregory P Cosgrove, Annie Clark, Scott M Turner, Martin Decaris, Chris N Barnes, Marzena Jurek, Brittney Williams and 6 more

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Annals of the American Thoracic Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Pulmonary Fibrosis-Focusing on the Future: Aspen Lung Conference 2024 Summary.American journal of respiratory cell and molecular biology · 2025
    Article
  7. Review
  8. Molecular Imaging of Pulmonary Fibrosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  9. Review
  10. LangerinClinical, cosmetic and investigational dermatology · 2025
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Joshua J MooneyDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, and.ORCID 0000-0002-4687-194X
Susan JacobsDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, and.ORCID 0000-0002-8808-0038
Éric A LefebvrePliant Therapeutics, Inc., South San Francisco, California; and.
Gregory P CosgrovePliant Therapeutics, Inc., South San Francisco, California; and.
Annie ClarkPliant Therapeutics, Inc., South San Francisco, California; and.
Scott M TurnerPliant Therapeutics, Inc., South San Francisco, California; and.
Martin DecarisPliant Therapeutics, Inc., South San Francisco, California; and.
Chris N BarnesPliant Therapeutics, Inc., South San Francisco, California; and.
Marzena JurekPliant Therapeutics, Inc., South San Francisco, California; and.
Brittney WilliamsNuclear Medicine and Molecular Imaging Division, Department of Radiology, Stanford University, Stanford, California.
Heying DuanNuclear Medicine and Molecular Imaging Division, Department of Radiology, Stanford University, Stanford, California.
Richard KimuraNuclear Medicine and Molecular Imaging Division, Department of Radiology, Stanford University, Stanford, California.
Gaia RizzoInvicro, London, United Kingdom.
Graham SearleInvicro, London, United Kingdom.
Mirwais WardakNuclear Medicine and Molecular Imaging Division, Department of Radiology, Stanford University, Stanford, California.
H Henry GuoNuclear Medicine and Molecular Imaging Division, Department of Radiology, Stanford University, Stanford, California.ORCID 0000-0001-5511-1750

Funding

Pliant Therapeutics, Inc.
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antigens, NeoplasmIdiopathic Pulmonary FibrosisIntegrinsLungAgedDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedPositron-Emission TomographyPositron Emission Tomography Computed TomographyAntigens, Neoplasmintegrin alphavbeta6Integrinsbexotegrastidiopathic pulmonary fibrosisintegrin αvβ6PET imagingreceptor occupancy

Identifiers

PMID39499805
PMCPMC11892667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.