Evidence map›Paper›PMID 39499643›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2024

Anatomical vs. electrophysiological approach for ablation of premature ventricular contractions originating from the left ventricular summit (ISESHIMA-SUMMIT Study).

Ryuta Watanabe, Koichi Nagashima, Yasuhiro Shirai, Takayuki Kitai, Takuya Okada, Michifumi Tokuda, Masato Fukunaga, Koumei Onuki, Yosuke Nakatani, Shingo Yoshimura and 20 more

Abstract readComparative Study
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. PVC termination time: a novel real-time predictor of ablation success.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Ryuta WatanabeDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0003-2664-7139
Koichi NagashimaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0003-2326-225X
Yasuhiro ShiraiDepartment of Cardiology, Disaster Medical Center, Tokyo, Japan.ORCID 0000-0001-6321-2797
Takayuki KitaiDepartment of Cardiology, Sapporo Cardio Vascular Clinic, Sapporo Heart Center, Sapporo, Japan.ORCID 0000-0003-2851-3038
Takuya OkadaDepartment of Clinical Engineering, Sapporo Cardiovascular Clinic, Sapporo Heart Center, Sapporo, Japan.ORCID 0000-0003-0226-9073
Michifumi TokudaDepartment of Cardiology, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0003-1960-5627
Masato FukunagaDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.ORCID 0000-0002-0230-4556
Koumei OnukiDepartment of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.ORCID 0009-0006-5569-972X
Yosuke NakataniDivision of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan.ORCID 0000-0002-5427-5048
Shingo YoshimuraDivision of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan.ORCID 0000-0003-2744-0738
Seiji TakatsukiDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-0251-5193
Kenji HashimotoDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-9758-4177
Shuhei YamashitaDepartment of Cardiology, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-6259-0697
Masafumi KatoDivision of Cardiology, Mie Heart Center, Meiwa, Japan.
Fumiya UchidaDivision of Cardiology, Mie Heart Center, Meiwa, Japan.
Seiji FukamizuDepartment of Cardiology, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.ORCID 0000-0002-0291-9702
Rintaro HojoDepartment of Cardiology, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.ORCID 0000-0001-6332-2355
Hitoshi MoriDepartment of Cardiology, Saitama Medical University International Medical Center, Saitama, Japan.ORCID 0000-0002-1172-2995
Kazuhisa MatsumotoDepartment of Cardiology, Saitama Medical University International Medical Center, Saitama, Japan.ORCID 0000-0002-5648-8135
Hiroyuki KatoDivision of Cardiology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.ORCID 0009-0008-5837-356X
Kazumasa SugaDivision of Cardiology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.ORCID 0000-0002-9694-1969
Taku SakuraiDivision of Cardiology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.
Yusuke SakamotoDepartment of Cardiology, Tosei General Hospital, Seto, Japan.ORCID 0000-0002-5959-1445
Tatsuya HayashiDivision of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.ORCID 0000-0002-8927-0730
Yuji WakamatsuDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0002-1540-8514
Shu HirataDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0003-0226-466X
Moyuru HirataDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0003-2701-486X
Masanaru SawadaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0002-9663-7617
Sayaka KurokawaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0002-7989-3985
Yasuo OkumuraDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Ohyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan.ORCID 0000-0002-2960-4241

Funding

Fukuda Foundation for Medical Technology
6 · The paper itself

Abstract

aimsCatheter ablation (CA) of idiopathic ventricular arrhythmias (VAs) from the epicardial left ventricular summit is challenging. The endocardial approach targets two sites: the endocardial closest site (ECS) to the epicardial earliest activation site (epi-EAS) and the endocardial earliest activation site (endo-EAS). We aimed to differentiate between cases where CA at the ECS was effective and where CA at the endo-EAS yielded success. METHODS AND

resultsFifty-eight patients (47 men; age 60 ± 13 years) were analysed with VAs in which the EAS was observed in the coronary venous system (CVS). Overall, VAs were successfully eliminated in 42 (72%) patients: 8 in the CVS, 8 where the ECS matched with the endo-EAS, 11 at the ECS, and 15 at the endo-EAS. A successful ECS ablation was associated with a shorter epi-EAS-ECS distance (10.2 ± 4.7 vs. 18.8 ± 5.3 mm; P < 0.001) and shorter epi-EAS-left main coronary trunk (LMT) ostial distance (20.3 ± 7.6 vs. 30.3 ± 8.4 mm; P = 0.005), with optimal cut-off values of ≤12.6 and ≤24.0 mm, respectively. A successful endo-EAS ablation was associated with an earlier electrogram at the endo-EAS [23 (8, 36) vs. 15 (0, 19) ms preceding the QRS; P < 0.001] and shorter epi-EAS-endo-EAS interval [6 (1, 8) vs. 22 (12, 25) ms; P < 0.001], with optimal cut-off values of ≥18 and ≤9 ms, respectively.

conclusionShorter anatomical distances between the epi-EAS and ECS, and between the epi-EAS and LMT ostium, predict a successful ECS ablation. The prematurity of the endo-EAS electrogram and a shorter interval between the epi-EAS and endo-EAS predicted a successful endo-EAS ablation.

Indexed as

Catheter AblationElectrophysiologic Techniques, CardiacVentricular Premature ComplexesAction PotentialsAgedEndocardiumFemaleHeart RateHeart VentriclesHumansMaleMiddle AgedTreatment OutcomeAnatomical approachElectrophysiological approachIdiopathic ventricular arrhythmiasLeft ventricular summit

Identifiers

PMID39499643
PMCPMC11572719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.