ArticleJournal of cosmetic dermatology2025
When to change needles during neuromodulator injections-An electron-microscopy investigation into needle tip deformation.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Comment on Article by Akintilo Et al.: When to Change Needles During Neuromodulator Injections-An Electron-Microscopy Investigation Into Needle Tip Deformation.Journal of cosmetic dermatology · 2025Article
- When to change needles during neuromodulator injections-An electron-microscopy investigation into needle tip deformation.Journal of cosmetic dermatology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuromodulator injections are minimally invasive procedures performed across the globe. Despite their ubiquity, there is a dearth of information on whether and how needle tips used for neuromodulator procedures are deformed after repeated injections.
objectiveWe investigated the magnitude of needle tip deformation following sequential injection passes (3×, 5×, and 10×) during facial neuromodulator injections with three commonly used needle sizes (30G, 31G, and 32G).
methodsNeuromodulator was administered for four different aesthetic indications. Each collected needle was mounted and imaged in a Philips XL-30 Scanning electron microscope. Images were processed using ImageJ photo analysis software.
resultsForty-five needle tips were investigated. When comparing the facial regions of interest, a statistically significant difference in deformation percentage was found when injecting 10× (p = 0.044) with greatest damage after injecting the glabella (38.4%), followed by lateral canthus (27.9%), forehead (27.5%), and midface (23.1%). Independent of facial region targeted, the mean percentage of needle deformation at 3× was 14.8%, at 5× 19.6%, and at 10× 29.2% with p < 0.001. Smaller needle size corresponded to smaller percentage of damage.
conclusionExchanging needles after more than five injection passes will minimize needle deformation and likely increase injection precision.
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