Evidence map›Paper›PMID 39499390›Full record

ArticleCell biochemistry and biophysics2025

Mechanism of the KIAA1429/KLF1/PD-L1 Axis in Regulating Immune Escape in Non-small Cell Lung Cancer.

Rui Geng, Mingmin Ren, Yuhui Ma, Wen Su

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Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. WTAP-mediated mMolecular genetics and genomics : MGG · 2026
    Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui GengDepartment of Research-oriented Ward, Yuncheng Central Hospital Affiliated to Shanxi Medical University, Yuncheng, Shanxi, China.
Mingmin RenDepartment of Research-oriented Ward, Yuncheng Central Hospital Affiliated to Shanxi Medical University, Yuncheng, Shanxi, China.
Yuhui MaDepartment of Cancer Center, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences; Tongji Shanxi Hospital, Tongji Medical College, Huazhong University Science of and Technology, Taiyuan, Shanxi, China.
Wen SuDepartment of Immunology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China. 13509731663@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC), accounting for approximately 80% of lung cancer cases, remains the leading cause of cancer-related mortality. Immune evasion is a critical challenge in NSCLC, contributing to poor treatment outcomes. This study investigates the role of KIAA1429 in immune evasion, aiming to identify novel therapeutic targets and provide a theoretical basis for NSCLC treatment. NSCLC cell lines were cultured to assess the expression of KIAA1429, KLF transcription factor (KLF1), and programmed cell death ligand 1 (PD-L1). Co-culture experiments were conducted with peripheral blood mononuclear cells (PBMCs) to evaluate cytotoxicity, CD8

Indexed as

B7-H1 AntigenCarcinoma, Non-Small-Cell LungKruppel-Like Transcription FactorsLung NeoplasmsTumor EscapeAdenosineCD8-Positive T-LymphocytesCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansInterferon-gammaInterleukin-10Leukocytes, MononuclearAdenosineB7-H1 AntigenCD274 protein, humanInterferon-gammaInterleukin-10Kruppel-Like Transcription FactorsN-methyladenosineImmune escapeKIAA1429KLF1m6ANSCLC

Identifiers

PMID39499390

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.