Evidence map›Paper›PMID 39499138›Full record

ArticleBioinformatics (Oxford, England)2024

ViralPrimer: a web server to monitor viral nucleic acid amplification tests' primer efficiency during pandemics, with emphasis on SARS-CoV-2 and Mpox.

Norbert Deutsch, Zsuzsanna Dosztányi, István Csabai, Anna Medgyes-Horváth, Orsolya Anna Pipek, József Stéger, Krisztián Papp, Dávid Visontai, Gábor Erdős, Anikó Mentes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Norbert DeutschDepartment of Biochemistry, Institute of Biology, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Zsuzsanna DosztányiDepartment of Biochemistry, Institute of Biology, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
István CsabaiDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Anna Medgyes-HorváthDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Orsolya Anna PipekDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
József StégerDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Krisztián PappDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Dávid VisontaiDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Gábor ErdősDepartment of Biochemistry, Institute of Biology, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.
Anikó MentesDepartment of Physics of Complex Systems, Institute of Physics and Astronomy, ELTE Eötvös Loránd University, Budapest H-1117, Hungary.ORCID 0000-0001-9559-374X

Funding

European Union 874735
6 · The paper itself

Abstract

summaryAccurate pathogen identification is crucial during outbreaks, especially with the emergence of new variants requiring frequent primer updates. However, resources for maintaining up-to-date verification of primer sequences are often limited, which poses challenges for reliable diagnosis and hinders potential monitoring efforts based on genome sequencing. To address this, we introduce ViralPrimer, a web server facilitating primer design, SARS-CoV-2 and Mpox variant monitoring, and adaptation to future threats. ViralPrimer aims to enhance diagnostic accuracy with its comprehensive primer database, mutation analysis assistance, and user primer upload feature. Its adaptable design allows monitoring of other rapidly mutating pathogens, contributing to broader public health protection efforts. AVAILABILITY AND IMPLEMENTATION: ViralPrimer is freely accessible and open to all users with no login requirement at https://viralprimer.elte.hu/. The application is hosted on a DJANGO v3.2.13 web server, with a PostgreSQL database, and the frontend was implemented using jQuery v3.6.0, vanilla JavaScript vES6, and Bootstrap v5.1.

Indexed as

COVID-19SARS-CoV-2SoftwareCOVID-19 Nucleic Acid TestingDNA PrimersHumansInternetMpox, MonkeypoxNucleic Acid Amplification TechniquesPandemicsDNA Primers

Identifiers

PMID39499138
PMCPMC11572492

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.