Evidence map›Paper›PMID 39499009›Full record

ReviewJournal of virology2024

Studying bats using a One Health lens: bridging the gap between bat virology and disease ecology.

Victoria Gonzalez, Arianna M Hurtado-Monzón, Sabrina O'Krafka, Elke Mühlberger, Michael Letko, Hannah K Frank, Eric D Laing, Kendra L Phelps, Daniel J Becker, Vincent J Munster and 4 more

Abstract readReview
In one paragraph

Review in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. 229E- and NL63-like coronaviruses in phyllostomid bats, Belize.One health (Amsterdam, Netherlands) · 2025
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Victoria Gonzalez *Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-6788-2939
Arianna M Hurtado-Monzón *Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Sabrina O'KrafkaVaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Elke MühlbergerDepartment of Virology, Immunology, and Microbiology, Boston University, Boston, Massachusetts, USA.ORCID 0000-0003-3547-9376
Michael LetkoPaul G. Allen School for Global Health, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-7640-2861
Hannah K FrankDepartment of Ecology and Evolutionary Biology, Tulane University, New Orleans, Louisiana, USA.
Eric D LaingDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, USA.
Kendra L PhelpsEcoHealth Alliance, New York, New York, USA.ORCID 0000-0002-3120-4802
Daniel J BeckerSchool of Biological Sciences, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0003-4315-8628
Vincent J MunsterLaboratory of Virology, National Institute of Allergy and Infectious Diseases (NIAID), Hamilton, Montana, USA.ORCID 0000-0002-2288-3196
Darryl FalzaranoVaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-8805-8068
Tony SchountzDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-1292-7650
Stephanie N SeifertPaul G. Allen School for Global Health, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-4397-6156
Arinjay BanerjeeVaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0002-2821-8357

Funding

Vascular-macrophage crosstalk in GBM immunosuppressionP20GM134973 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Sree Deepthi Muthukrishnan · 2020 to 2026
$17.6M
Emerging Infectious Diseases Research Center - East and Central AfricaU01AI151799 · NIAID · WASHINGTON STATE UNIVERSITY · PI M KARIUKI NJENGA · 2020 to 2026
$10.4M
MERS coronavirus: antagonism of double-stranded RNA induced host response by accessory proteinsR01AI140442 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Susan R Weiss · 2018 to 2026
$5.1M
Establishment of a Bat Resource for Infectious Disease ResearchR24AI165424 · NIAID · COLORADO STATE UNIVERSITY · PI SCHOUNTZ, WILLIAM A · 2023 to 2024
$4.0M
Biology and infection of bats with novel bat influenza virusesR01AI134768 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI MA, WENJUN · 2018 to 2022
$2.1M
Functional Viromics of Betacoronavirus EntryR01AI179720 · NIAID · WASHINGTON STATE UNIVERSITY · PI Barbara A. Han, Michael Letko · 2024 to 2026
$1.1M
Deciphering the pathogenic potential of Lloviu virus, a novel filovirusR21AI137793 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MUHLBERGER, ELKE C · 2018 to 2019
$453k
Development and function of humoral immunity in the Jamaican fruit bat, Artibeus jamaicensisR21AI169548 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI FRANK, HANNAH KIM, SCHOUNTZ, WILLIAM A · 2022 to 2023
$431k
Elucidating the immune response of Schreiber's bats to Lloviu virus infection in vitro and in vivoR21AI169646 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MUHLBERGER, ELKE C · 2022 to 2023
$430k
Assessing the interferome in novel, purpose-driven bat-derived cellsR21AI169527 · NIAID · WASHINGTON STATE UNIVERSITY · PI BANERJEE, ARINJAY, LETKO, MICHAEL · 2022 to 2023
$362k
NIAID NIH HHS R01 AI134768NIAID NIH HHS R01 AI140442NIAID NIH HHS R01 AI179720NIAID NIH HHS R21 AI137793NIAID NIH HHS R21 AI169527NIAID NIH HHS R21 AI169548NIAID NIH HHS R21 AI169646NIAID NIH HHS R24 AI165424NIAID NIH HHS U01 AI151799NIGMS NIH HHS P20 GM134973
6 · The paper itself

Abstract

Accumulating data suggest that some bat species host emerging viruses that are highly pathogenic in humans and agricultural animals. Laboratory-based studies have highlighted important adaptations in bat immune systems that allow them to better tolerate viral infections compared to humans. Simultaneously, ecological studies have discovered critical extrinsic factors, such as nutritional stress, that correlate with virus shedding in wild-caught bats. Despite some progress in independently understanding the role of bats as reservoirs of emerging viruses, there remains a significant gap in the molecular understanding of factors that drive virus spillover from bats. Driven by a collective goal of bridging the gap between the fields of bat virology, immunology, and disease ecology, we hosted a satellite symposium at the 2024 American Society for Virology meeting. Bringing together virologists, immunologists, and disease ecologists, we discussed the intrinsic and extrinsic factors such as virus receptor engagement, adaptive immunity, and virus ecology that influence spillover from bat hosts. This article summarizes the topics discussed during the symposium and emphasizes the need for interdisciplinary collaborations and resource sharing.

Indexed as

ChiropteraDisease ReservoirsOne HealthAdaptive ImmunityAnimalsCongresses as TopicEcologyHumansVirologyVirus DiseasesASV 2024batsdisease ecologyimmunitysatellite symposiumvirology

Identifiers

PMID39499009
PMCPMC11650978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.