Evidence map›Paper›PMID 39498757›Full record

ReviewJapanese journal of clinical oncology2025

The role of external-beam radiotherapy for differentiated thyroid cancer.

Terufumi Kawamoto, Naoto Shikama, Naoki Nakamura, Takashi Mizowaki

Abstract readReview
In one paragraph

Review in Japanese journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Terufumi KawamotoDepartment of Radiation Oncology, Juntendo University, Graduate School of Medicine, Tokyo, Japan.ORCID 0000-0001-9014-5577
Naoto ShikamaDepartment of Radiation Oncology, Juntendo University, Graduate School of Medicine, Tokyo, Japan.
Naoki NakamuraDepartment of Radiation Oncology, St. Marianna University School of Medicine Hospital, Kyoto, Kanagawa, Japan.
Takashi MizowakiDepartment of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0002-8135-8746

Funding

JSPS KAKENHI JP23K14926
6 · The paper itself

Abstract

The treatment options for differentiated thyroid cancer (DTC) are surgery, thyroid stimulating hormone suppression, radioactive iodine, and multitargeted tyrosine kinase inhibitors. The role of external-beam radiotherapy (EBRT) for DTC is controversial because of the lack of randomized controlled trials, but prospective single-arm studies and propensity score matching analyses have shown its efficacy and safety. This review discusses the role of EBRT after resection of gross disease, when there is a high risk of locoregional failure, as well as its role for locoregionally gross recurrent and unresectable disease. As in other tumor sites, EBRT has an important role in the palliative management and local control of patients with metastatic DTC, especially with bone and brain metastases.

Indexed as

Thyroid NeoplasmsBrain NeoplasmsHumansNeoplasm Recurrence, Localadjuvant therapyintensity-modulated radiotherapypalliative therapystereotactic radiation therapythyroid carcinoma

Identifiers

PMID39498757
PMCPMC11792076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.