Evidence map›Paper›PMID 39498480›Full record

ArticleDevelopment and psychopathology2025

Family income and polygenic scores are independently but not interactively associated with cognitive performance among youth genetically similar to European reference populations.

S E Paul, N M Elsayed, S M C Colbert, R Bogdan, A S Hatoum, D M Barch

Abstract read
In one paragraph

Article in Development and psychopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S E Paul *Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.
N M Elsayed *Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.ORCID https://orcid.org/0009-0009-5260-1311
S M C ColbertDepartment of Psychiatry, Washington University School of Medicine, St. Louis, USA.
R BogdanDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.
A S HatoumDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.
D M BarchDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, USA.

Funding

Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
Neurobehavioral pathways of polygenic and polyenvironmental effects on the onset and maintenance of substance involvementR01DA054750 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA, BOGDAN, RYAN H · 2021 to 2025
$2.0M
Mass Multivariate Derivation and Validation of AUD Biotypes using Developmental Imaging and Genomic ApproachesK01AA030083 · NIAAA · WASHINGTON UNIVERSITY · PI Alexander S Hatoum · 2022 to 2026
$897k
Trajectories of Alcohol Involvement from Middle Childhood to Early Adulthood: A Multimodal InvestigationF31AA029934 · NIAAA · WASHINGTON UNIVERSITY · PI PAUL, SARAH EMILY · 2021 to 2023
$121k
NIAAA NIH HHS F31 AA029934NIAAA NIH HHS K01 AA030083NIDA NIH HHS R01 DA054750NIDA NIH HHS U01 DA041120
6 · The paper itself

Abstract

Cognitive abilities are heritable and influenced by socioeconomic status (SES). It is critical to understand the association between SES and cognition beyond genetic propensity to inform potential benefits of SES-based interventions and to determine if such associations vary across (i) cognitive domains, (ii) facets of SES, and/or (iii) genetic propensity for different aspects of cognition. We examined the contributions of neighborhood socioeconomic advantage, family income, and polygenic scores (PGS) for domains of cognition (i.e., general cognitive ability, executive function, learning and memory, fluid reasoning) in a sample of children (ages 9-10;

Indexed as

CognitionIncomeMultifactorial InheritanceSocial ClassChildEuropeExecutive FunctionFemaleHumansMaleNeuropsychological TestsWhite Peoplecognitive abilityfamilial incomegene-environment interactionneighborhood advantagepolygenic risk scores

Identifiers

PMID39498480
PMCPMC12186736

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.