Evidence map›Paper›PMID 39498389›Full record

ArticleFrontiers in neuroimaging2024

Iron load in the normal aging brain measured with QSM and

Miguel Guevara, Stéphane Roche, Vincent Brochard, Davy Cam, Jacques Badagbon, Yann Leprince, Michel Bottlaender, Yann Cointepas, Jean-François Mangin, Ludovic de Rochefort and 1 more

Abstract read
In one paragraph

Article in Frontiers in neuroimaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miguel GuevaraUniversité Paris-Saclay, CEA, CNRS, BAOBAB, Neurospin, Gif-sur-Yvette, France.
Stéphane RocheVENTIO, Marseille, France.
Vincent BrochardUniversité Paris-Saclay, CEA, Neurospin, UNIACT, Gif-sur-Yvette, France.
Davy CamVENTIO, Marseille, France.
Jacques BadagbonVENTIO, Marseille, France.
Yann LeprinceUniversité Paris-Saclay, CEA, CNRS, BAOBAB, Neurospin, Gif-sur-Yvette, France.
Michel BottlaenderUniversité Paris-Saclay, CEA, Neurospin, UNIACT, Gif-sur-Yvette, France.
Yann CointepasUniversité Paris-Saclay, CEA, CNRS, BAOBAB, Neurospin, Gif-sur-Yvette, France.
Jean-François ManginUniversité Paris-Saclay, CEA, CNRS, BAOBAB, Neurospin, Gif-sur-Yvette, France.
Ludovic de RochefortVENTIO, Marseille, France.
Alexandre VignaudUniversité Paris-Saclay, CEA, CNRS, BAOBAB, Neurospin, Gif-sur-Yvette, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Iron accumulates in the brain during aging and is the focus of intensive research as an abnormal load, particularly in Deep Gray Matter (DGM), is related to neurodegeneration. Magnetic Resonance Imaging (MRI) metrics such as Quantitative Susceptibility Mapping (QSM) and apparent transverse relaxation rate Methods: QSM and Results: Age and sex have an influence on the brain iron deposition measured by QSM and Conclusions: Establishing baseline values of QSM and

Indexed as

brain irondeep gray matterhealthy brain agingQSMR*2

Identifiers

PMID39498389
PMCPMC11533018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.