Different implications of daytime and nighttime heart rate variability on total burden of cerebral small vascular disease in patients with nondisabling ischemic cerebrovascular events.

Zhixiang Zhang, Yijun Lv, Qian Wang, Yan Wang, Min Zhang, Yongjun Cao

Abstract read

In one paragraph

Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhixiang Zhang *Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Yijun Lv *Department of Neurology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Medical Center of Nanjing Medical University, Changzhou, China.

Qian WangDepartment of Neurology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Medical Center of Nanjing Medical University, Changzhou, China.

Yan WangDepartment of Neurology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Medical Center of Nanjing Medical University, Changzhou, China.

Min ZhangDepartment of Neurology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou Medical Center of Nanjing Medical University, Changzhou, China.

Yongjun CaoDepartment of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to explore the relationship between total burden of cerebral small vessel disease (CSVD) and daytime and nighttime heart rate variability (HRV) parameters. Method: Consecutive patients with nondisabling ischemic cerebrovascular events were recruited from the cerebrovascular disease clinic of Changzhou Second People's Hospital between January 2022 and June 2023. A total of 144 enrolled participants were divided into a mild CSVD group (74 patients) and a moderate-to-severe CSVD group (70 patients) based on total burden of CSVD. Various HRV parameters measured during 24-h, 4-h daytime, and 4-h nighttime periods (including natural log-transformed [ln] root mean square of successive RR interval differences [RMSSD], ln absolute power of the high-frequency band [0.15-0.4 Hz] [HF], ln absolute power of the low-frequency band [0.04-0.15 Hz][LF], and LF-to-HF ratio [LF/HF]) were then assessed in the 2 groups. Spearman correlation analysis was used to assess the correlation between total burden of CSVD and HRV parameters. HRV parameters with Results: Daytime 4-h lnRMSSD (r = -0.221; Conclusion: Daytime parasympathetic HRV parameters are independent influencing factors of total burden of CSVD and may serve as potential therapeutic observation indicators for CSVD.

Indexed as

cerebral small vessel diseasedaytimeheart rate variabilitynighttimenondisabling ischemic cerebrovascular eventstotal burden

Identifiers

PMID39498356

DOI10.3389/fcvm.2024.1434041

PMCPMC11532077

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.