Evidence map›Paper›PMID 39498148›Full record

ReviewMaterials today. Bio2024

The considerations on selecting the appropriate decellularized ECM for specific regeneration demands.

Shihan Zhang, Yaru Guo, Yixuan Lu, Fangyong Liu, Boon Chin Heng, Xuliang Deng

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Moving Toward Biomimetic Tissue-Engineered Scaffolds.Nanomaterials (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shihan ZhangDepartment of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Yaru GuoDepartment of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Yixuan LuDepartment of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Fangyong LiuDepartment of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Boon Chin HengCentral Laboratory, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Xuliang DengDepartment of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, 100081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An ideal biomaterial should create a customized tissue-specific microenvironment that can facilitate and guide the tissue repair process. Due to its good biocompatibility and similar biochemical properties to native tissues, decellularized extracellular matrix (dECM) generally yields enhanced regenerative outcomes, with improved morphological and functional recovery. By utilizing various decellularization techniques and post-processing protocols, dECM can be flexibly prepared in different states from various sources, with specifically customized physicochemical properties for different tissues. To initiate a well-orchestrated tissue-regenerative response, dECM exerts multiple effects at the wound site by activating various overlapping signaling pathways to promote cell adhesion, proliferation, and differentiation, as well as suppressing inflammation via modulation of various immune cells, including macrophages, T cells, and mastocytes. Functional tissue repair is likely the main aim when employing the optimized dECM biomaterials. Here, we review the current applications of different kinds of dECMs in an attempt to improve the efficiency of tissue regeneration, highlighting key considerations on developing dECM for specific tissue engineering applications.

Indexed as

Decellularized extracellular matrix biomaterialsPhysicochemical propertiesTissue engineeringUnderlying mechanisms on dECM-mediated regeneration process

Identifiers

PMID39498148
PMCPMC11532911

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.