Evidence map›Paper›PMID 39497952›Full record

ArticleHeliyon2024

Clarification of a unique mucosal vaccination route for improved systemic and mucosal immune response in broiler.

Rupa Akter, Md Abdul Masum, Subrato Biswas, Md Zahir Uddin Rubel, Sujan Kumar Sarkar, Mohammad Saiful Islam, Hossain M Golbar, Md Emtiaj Alam, Md Abdur Rakib, Md Zahirul Isalm Khan

Abstract read
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In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rupa AkterDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Md Abdul MasumDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Subrato BiswasDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Md Zahir Uddin RubelDepartment of Poultry Science, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Sujan Kumar SarkarDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Mohammad Saiful IslamDepartment of Anatomy, Histology & Physiology, Sher-e-Bangla Agricultural University, Dhaka, 1207, Bangladesh.
Hossain M GolbarDepartment of Veterinary and Animal Sciences, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md Emtiaj AlamDepartment of Veterinary and Animal Sciences, University of Rajshahi, Rajshahi, 6205, Bangladesh.
Md Abdur RakibQuality Assurance, Beximco Pharmaceuticals Limited, Dhaka, 1700, Bangladesh.
Md Zahirul Isalm KhanDepartment of Pre-Clinical courses, Gono Bishwabidyalay, Dhaka, 1344, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are often outbreaks of infectious diseases on farms, which not only disrupt production but also cause significant economic losses. Vaccines are given to prevent the spread of these infectious diseases, but they produce only systemic antibodies or antibodies in the mucosa of a particular system. So, a new mucosal vaccination route is needed where the vaccine will produce antibodies in the systemic circulation as well as in the mucosa of many systems. In our study, the cloaca was targeted because it is associated with the mucosa of many systems. Whole-mount and routine histological staining show both lymphatic nodules and diffuse lymphatic tissues in the lamina propria of cloaca. These lymphatic tissues are made up of Bu-1+ B-cells, CD3

Indexed as

BroilerCloacaImmune responseMucosaVaccine

Identifiers

PMID39497952
PMCPMC11532882

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.