Evidence map›Paper›PMID 39497871›Full record

ArticleCureus2024

Multilevel En-Bloc Excision of Thoracic Spine Primary Chondrosarcoma Through an All-Posterior Approach: A Report of Two Cases.

Rodrigo Muscogliati, Nigil Palliyil, Daniel Shou Chien Chin, Kedar Deogaonkar, Mohammad Daher, Elie Najjar, Nasir Quraishi

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In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rodrigo MuscogliatiCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Nigil PalliyilCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Daniel Shou Chien ChinCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Kedar DeogaonkarCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Mohammad DaherCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Elie NajjarCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Nasir QuraishiCentre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondrosarcomas are malignant, cartilage-forming neoplasms. As these tumours are resistant to chemotherapy and radiotherapy, en-bloc excision of the tumour with wide margins is the only option that provides maximum disease-free survival and possible cure. We present two cases of primary chondrosarcoma of the thoracic spine treated by multilevel en-bloc excision through an all-posterior approach. Case 1 describes a 48-year-old female who presented with mid-back pain for six months. MRI revealed an expansile lesion between T9 and T11; a biopsy confirmed this to be chondrosarcoma. Following a posterior-only approach, the entire tumour mass with the overlying pleura, part of the T9-T11 vertebral body and the posterior elements, as well as the posteromedial part of the ninth, tenth, and eleventh ribs, were removed en bloc. Case 2 describes a 29-year-old male who presented with mid-back pain for five months. MRI revealed a lesion at T10, which was later confirmed on histopathological examination to be chondrosarcoma, affecting T9-T11. Using a posterior-only approach, the entire tumour mass, with part of T8-T11 was delivered en bloc. Both patients made an uneventful recovery, and there were no signs of disease at 24 months post-operatively. Despite being technically demanding, multilevel en-bloc tumour resection of the spine remains the mainstay in certain primary tumours, as it is potentially curative. Although the overall complication percentage following multilevel en-bloc resections was high, the local recurrence rate was significantly low. While most published articles recommend a posterior-only approach for limited disease, the cases in this report suggest that a posterior-only approach could also be viable for select cases of multilevel chondrosarcoma.

Indexed as

chondrosarcoma spinemultilevel en-bloc spondylectomyposterior only approach for spine en-bloc tumour excisionthoracic spine tumourwide excision of spine tumours

Identifiers

PMID39497871
PMCPMC11533881

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