Evidence map›Paper›PMID 39497836›Full record

ArticleLancet regional health. Americas2024

Clinical profile of patients with acute traumatic brain injury undergoing cranial surgery in the United States: report from the 18-centre TRACK-TBI cohort study.

John K Yue, John H Kanter, Jason K Barber, Michael C Huang, Thomas A van Essen, Mahmoud M Elguindy, Brandon Foreman, Frederick K Korley, Patrick J Belton, Dana Pisică and 34 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lancet regional health. Americas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02119182 (Transforming Research and Clinical Knowledge in Traumatic Brain Injury), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02119182 completednot on this map

Transforming Research and Clinical Knowledge in Traumatic Brain Injury

TypeobservationalSponsorUniversity of California, San FranciscoRan2014 to 2020Enrolled2,996ConditionsTraumatic Brain InjuryArmsIn-Person Outcome Assessment, Phone Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Blood Draw for Plasma, DNA, Serum, RNA
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

John K YueDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
John H KanterDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Jason K BarberDepartments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA, United States.
Michael C HuangDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Thomas A van EssenUniversity Neurosurgical Center Holland, Leiden University Medical Center, Haaglanden Medical Center, HAGA, Leiden, The Hague, the Netherlands.
Mahmoud M ElguindyDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Brandon ForemanDepartment of Neurology, University of Cincinnati, Cincinnati, OH, United States.
Frederick K KorleyDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MI, United States.
Patrick J BeltonDepartment of Neurological Surgery, University of Wisconsin-Madison, Madison, WI, United States.
Dana PisicăCenter for Medical Decision Making, Department of Epidemiology and Public Health, Erasmus MC, University Center Rotterdam, Rotterdam, the Netherlands.
Young M LeeDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Ryan S KitagawaDepartment of Neurological Surgery, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Mary J VassarDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Xiaoying SunBiostatistics Research Center, Herbert Wertheim School of Public Health and Longevity Science, University of California San Diego, La Jolla, CA, United States.
Gabriela G SatrisDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Justin C WongDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Adam R FergusonDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
J Russell HuieDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Kevin K W WangDepartment of Neurobiology, Morehouse School of Medicine, Atlanta, GA, United States.
Hansen DengDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Vincent Y WangDepartment of Neurological Surgery, University of Texas at Austin, Austin, TX, United States.
Yelena G BodienDepartment of Neurology, Harvard Medical School, Boston, MA, United States.
Sabrina R TaylorDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Debbie Y MadhokDepartments of Emergency Medicine and Neurology, University of California, San Francisco, San Francisco, CA, United States.
Michael A McCreaDepartment of Neurological Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.
Laura B NgwenyaDepartment of Neurological Surgery, University of Cincinnati, Cincinnati, OH, United States.
Anthony M DiGiorgioDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Phiroz E TaraporeDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Murray B SteinDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Ava M PuccioDepartment of Neurobiology, Morehouse School of Medicine, Atlanta, GA, United States.
Joseph T GiacinoDepartment of Rehabilitation Medicine, Spaulding Rehabilitation Center, Boston, MA, United States.
Ramon Diaz-ArrastiaDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Hester F LingsmaCenter for Medical Decision Making, Department of Epidemiology and Public Health, Erasmus MC, University Center Rotterdam, Rotterdam, the Netherlands.
Pratik MukherjeeBrain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.
Esther L YuhBrain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.
Claudia S RobertsonDepartment of Neurological Surgery, Baylor College of Medicine, Houston, TX, United States.
David K MenonDivision of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Andrew I R MaasDepartment of Neurological Surgery, Antwerp University Hospital, Edegem, Belgium.
Amy J MarkowitzDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Sonia JainBiostatistics Research Center, Herbert Wertheim School of Public Health and Longevity Science, University of California San Diego, La Jolla, CA, United States.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Nancy R TemkinDepartments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA, United States.
Geoffrey T ManleyDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
TRACK-TBI Investigators

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDWARD C HSIAO · 2019 to 2026
$7.1M
Transforming Traumatic Brain Injury Research and Clinical CareRC2NS069409 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MANLEY, GEOFFREY T · 2009 to 2011
$4.3M
NIAMS NIH HHS P30 AR075055NINDS NIH HHS RC2 NS069409NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

Background: Contemporary surgical practices for traumatic brain injury (TBI) remain unclear. We describe the clinical profile of an 18-centre US TBI cohort with cranial surgery. Methods: The prospective, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (2014-2018; ClinicalTrials.gov #NCT02119182) enrolled subjects who presented to trauma centre and received head computed tomography within 24-h (h) post-TBI. We performed a secondary data analysis in subjects aged ≥17-years with hospitalisation. Clinical characteristics, surgery type/timing, hospital and six-month outcomes were reported. Findings: Of 2032 subjects (age: mean = 41.4-years, range = 17-89-years; male = 71% female = 29%), 260 underwent cranial surgery, comprising 65% decompressive craniectomy, 23% craniotomy, 12% other surgery. Subjects with surgery (vs. without surgery) presented with worse neurological injury (median Glasgow Coma Scale = 6 vs. 15; midline shift ≥5 mm: 48% vs. 2%; cisternal effacement: 61% vs. 4%; p < 0.0001). Median time-to-craniectomy/craniotomy was 1.8 h (interquartile range = 1.1-5.0 h), and 67% underwent intracranial pressure monitoring. Seventy-three percent of subjects with decompressive craniectomy and 58% of subjects with craniotomy had ≥3 intracranial lesion types. Decompressive craniectomy (vs. craniotomy) was associated with intracranial injury severity (median Rotterdam Score = 4 vs. 3, p < 0.0001), intensive care length of stay (median = 13 vs. 4-days, p = 0.0002), and six-month unfavourable outcome (62% vs. 30%; p = 0.0001). Earlier time-to-craniectomy was associated with intracranial injury severity. Interpretation: In a large representative cohort of patients hospitalised with TBI, surgical decision-making and time-to-surgery aligned with intracranial injury severity. Multifocal TBIs predominated in patients with cranial surgery. These findings summarise current TBI surgical practice across US trauma centres and provide the foundation for analyses in targeted subpopulations. Funding: National Institute of Neurological Disorders and Stroke; US Department of Defense; Neurosurgery Research and Education Foundation.

Indexed as

CraniotomyDecompressive craniectomyGlasgow outcome scaleMedical decisionmakingNeuroimagingTraumatic brain injuryTraumatic intracranial hemorrhageTriage

Identifiers

PMID39497836
PMCPMC11532273

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Registered trials

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