Evidence map›Paper›PMID 39497830›Full record

ArticleFrontiers in immunology2024

Lesional senescent CD4

Luciana Polaco Covre, Carlos Henrique Fantecelle, Renan Garcia de Moura, Paola Oliveira Lopes, Isabela Valim Sarmento, Celio Geraldo Freire-de-Lima, Debora Decote-Ricardo, Herbert Leonel de Matos Guedes, Alessandra Marcia da Fonsceca-Martins, Lucas Pedreira de Carvalho and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luciana Polaco CovreNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.
Carlos Henrique FantecelleNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.
Renan Garcia de MouraNúcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.
Paola Oliveira LopesNúcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.
Isabela Valim SarmentoNúcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.
Celio Geraldo Freire-de-LimaInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Debora Decote-RicardoDepartamento de Veterinária, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro, Brazil.
Herbert Leonel de Matos GuedesInstituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Alessandra Marcia da Fonsceca-MartinsInstituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Lucas Pedreira de CarvalhoLaboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil.
Edgar Marcelino de CarvalhoLaboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil.
David M MosserDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States.
Aloisio FalquetoDepartamento de Medicina Social, Universidade Federal do Espírito Santo, Vitória, Brazil.
Arne N AkbarDivision of Medicine, University College London, London, United Kingdom.
Daniel Claudio Oliveira GomesNúcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.

Funding

Host and parasite factors promoting disease and treatment failure in Leishmania braziliensis patientsR01AI149456 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CARVALHO, LUCAS P, SCOTT, PHILLIP · 2020 to 2023
$626k
NIAID NIH HHS R01 AI149456
6 · The paper itself

Abstract

Cytotoxic activity is a hallmark of the immunopathogenesis in human cutaneous leishmaniasis (CL). In this study, we identified accumulation of CD4

Indexed as

CD4-Positive T-LymphocytesCellular SenescenceLeishmaniasis, CutaneousSkinAdultBystander EffectCytotoxicity, ImmunologicFemaleGranzymesHumansMaleMiddle AgedT-Lymphocytes, CytotoxicYoung AdultGranzymesGZMB protein, humanbystander cytotoxicityCD4-CTLcutaneous leishmaniasisLeishmania braziliensissenescent cells

Identifiers

PMID39497830
PMCPMC11532160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.