Evidence map›Paper›PMID 39497819›Full record

ArticleFrontiers in immunology2024

A co-culture model to study modulators of tumor immune evasion through scalable arrayed CRISPR-interference screens.

Ramiro Martinez, Chiara Finocchiaro, Louis Delhaye, Fien Gysens, Jasper Anckaert, Wim Trypsteen, Maarten Versteven, Eva Lion, Sandra Van Lint, Karim Vermaelen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ramiro MartinezOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Chiara FinocchiaroOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Louis DelhayeOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Fien GysensOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Jasper AnckaertOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Wim TrypsteenOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Maarten VerstevenLaboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Eva LionLaboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Sandra Van LintCancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.
Karim VermaelenCancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.
Eric James de BonyOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.
Pieter MestdaghOncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cells effectively evade immune surveillance, not only through the well-known PD-1/PD-L1 pathway but also

Indexed as

Coculture TechniquesCRISPR-Cas SystemsMelanomaTumor EscapeCell Line, TumorClustered Regularly Interspaced Short Palindromic RepeatsHumansT-Lymphocytesarrayed screensco-cultureCRISPRiimmuno-oncologylong non-coding RNAs

Identifiers

PMID39497819
PMCPMC11532180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.