SynthesisFrontiers in neurology2024
Association of hearing loss and risk of depression: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Suicidality in Individuals With Hearing Loss: A Systematic Review and Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Pooled it
- Specificity of environmental risk factors for schizophrenia, bipolar disorders, and depressive disorders - umbrella review.Psychological medicine · 2025Pooled it
- A Moderated Mediation Model Linking Speech-in-Noise Exposure, Speech Perception in Noise Ability, Loneliness, and Depression.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Article
- Machine learning-based risk classification of depressive symptoms among patients with hearing loss: evidence from the Health and Retirement Study (HRS).Comprehensive psychoneuroendocrinology · 2026Article
- Workforce Sustainability in Audiology: Evidence, Challenges, and a Roadmap to Autonomy.Seminars in hearing · 2026Article
- The association between hearing impairment and incident depression in older adults: a longitudinal analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Depressive Symptoms and Risk of Hearing Loss Among Adults Aged 55 Years and Older: A Population-Based Study.Balkan medical journal · 2026Observational
- Degree, Pattern, and Risk Factors of Hearing Loss Among Adults of Eastern India.Journal of audiology & otology · 2026Article
- Association of vitamin D deficiency with incident depression in patients with hearing impairment: an observational retrospective cohort study.Frontiers in nutrition · 2026Article
- When Sound Fades: Depression and Anxiety in Adults with Hearing Loss-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Relationship between age-related hearing loss and alcohol consumption in a Japanese population.Scientific reports · 2025Article
- Prevalence of self-reported hearing loss and its association with depression in individuals aged 15 years and above in a large-scale representative sample: evidence from a nationwide population-based cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- The association between hearing loss and depression in the China health and retirement longitudinal study.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Previous studies have suggested a possible link between hearing loss and the risk of depression. However, the strength of this association remains uncertain across varying follow-up periods, age groups, cohort studies, and longitudinal study designs. Methods: We conducted an extensive literature search across PubMed, Embase, and the Cochrane Library databases to retrieve pertinent studies. The quality of observational studies was assessed using the Newcastle-Ottawa Scale. Synthesis and meta-analysis of odds ratios (ORs) along with corresponding 95% confidence intervals (CIs) were performed using Stata 14.0. Funnel plot analysis and Egger's regression test were utilized to assess potential publication bias. Results: This meta-analysis comprised 24 cohort studies conducted between 2007 and 2024, with sample sizes ranging from 548 to 254,466 participants. Among these participants, 24,304 had experienced depression events. The pooling analysis shows that hearing loss is associated with an increased risk of depression (OR = 1.35; 95%CI: 1.27-1.44). In the subgroup analysis, the retrospective cohort exhibited a slightly higher risk of depression compared to the prospective cohort (OR = 1.43; 95% CI: 1.30-1.58). There are differences in the risk of depression among young, middle-aged, and older individuals, with older adults facing a higher risk (OR = 1.33, 95% CI: 1.21-1.45). Additionally, the risk of depression was slightly higher in the sudden sensorineural hearing loss (SSNHL) group compared to the non-SSNHL group (OR = 1.62; 95% CI: 1.27-2.07). Furthermore, in cohorts with a follow-up time ≥ 5 years, the risk of depression was higher compared to those with <5 years of follow-up (OR = 1.39; 95% CI: 1.26-1.54). Conclusion: Our meta-analysis shows that hearing loss increases the risk of depression. These findings provide evidence that hearing loss should be recognized as an independent risk factor for depression. Clinical trial registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42024502043.
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