Evidence map›Paper›PMID 39497458›Full record

ReviewThe British journal of psychiatry : the journal of mental science2024

Detection of suicidality from medical text using privacy-preserving large language models.

Isabella Catharina Wiest, Falk Gerrik Verhees, Dyke Ferber, Jiefu Zhu, Michael Bauer, Ute Lewitzka, Andrea Pfennig, Pavol Mikolas, Jakob Nikolas Kather

Abstract readReview
In one paragraph

Review in The British journal of psychiatry : the journal of mental science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Isabella Catharina WiestElse Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany; and Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID https://orcid.org/0009-0004-4848-614X
Falk Gerrik VerheesDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.
Dyke FerberElse Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; and Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Jiefu ZhuElse Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
Michael BauerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.
Ute LewitzkaDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.
Andrea PfennigDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.
Pavol MikolasDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University Dresden, Dresden, Germany.
Jakob Nikolas KatherElse Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany; and Department of Medicine I, University Hospital Dresden, Dresden, Germany.

Funding

HORIZON EUROPE Excellent Science 101096312
6 · The paper itself

Abstract

backgroundAttempts to use artificial intelligence (AI) in psychiatric disorders show moderate success, highlighting the potential of incorporating information from clinical assessments to improve the models. This study focuses on using large language models (LLMs) to detect suicide risk from medical text in psychiatric care.

aimsTo extract information about suicidality status from the admission notes in electronic health records (EHRs) using privacy-sensitive, locally hosted LLMs, specifically evaluating the efficacy of Llama-2 models.

methodWe compared the performance of several variants of the open source LLM Llama-2 in extracting suicidality status from 100 psychiatric reports against a ground truth defined by human experts, assessing accuracy, sensitivity, specificity and F1 score across different prompting strategies.

resultsA German fine-tuned Llama-2 model showed the highest accuracy (87.5%), sensitivity (83.0%) and specificity (91.8%) in identifying suicidality, with significant improvements in sensitivity and specificity across various prompt designs.

conclusionsThe study demonstrates the capability of LLMs, particularly Llama-2, in accurately extracting information on suicidality from psychiatric records while preserving data privacy. This suggests their application in surveillance systems for psychiatric emergencies and improving the clinical management of suicidality by improving systematic quality control and research.

Indexed as

Electronic Health RecordsNatural Language ProcessingSuicideArtificial IntelligenceHumansMental DisordersSensitivity and Specificityelectronic health recordsLarge language modelsnatural language processingpsychiatric disorder detectionsuicidality

Identifiers

PMID39497458
PMCPMC11669470

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.