ArticleMagnetic resonance in medicine2025
Giving the prostate the boost it needs: Spiral diffusion MRI using a high-performance whole-body gradient system for high b-values at short echo times.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Diffusion MRI of the Body: Beyond PGSE-EPI.Journal of magnetic resonance imaging : JMRI · 2026Review
- Technical Feasibility of IVIM for Prostate Cancer Imaging Using High-Amplitude Whole-Body Gradient System With Spiral Readout and Velocity-Compensated Diffusion Encoding.NMR in biomedicine · 2026Article
- Microstructure imaging of prostate cancer by diffusion MRI.Magma (New York, N.Y.) · 2026Review
- Toward Super-Resolution Reconstruction of Diffusion-Relaxation MRI Using Slice Excitation With Random Overlap (SERO).Magnetic resonance in medicine · 2026Article
- Strong-Gradient Diffusion-Weighted Imaging of Prostate Cancer Using an Inside-Out Nonlinear Gradient Coil.Magnetic resonance in medicine · 2026Article
- Cartesian MaxGIRF: Model-based EPI reconstruction incorporating gradient nonlinearity and concomitant field effects.Magnetic resonance in medicine · 2026Article
- Giving the prostate the boost it needs: Spiral diffusion MRI using a high-performance whole-body gradient system for high b-values at short echo times.Magnetic resonance in medicine · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
purposeTo address key issues of low SNR and image distortions in prostate diffusion MRI (dMRI) by means of using strong gradients, single-shot spiral readouts and an expanded encoding model for image reconstruction.
methodsDiffusion-weighted spin echo imaging with EPI and spiral readouts is performed on a whole-body system equipped with strong gradients (up to 250 mT/m). An expanded encoding model including static off-resonance, coil sensitivities, and magnetic field dynamics is employed for image reconstruction. The acquisitions are performed on a phantom and in vivo (one healthy volunteer and one patient with prostate cancer). The resulting images are compared to conventional dMRI EPI with navigator-based image reconstruction and assessed in terms of their congruence, SNR, tissue contrast, and quantitative parameters.
resultsUsing the expanded encoding model, high-quality images of the prostate gland are obtained across all b-values (up to 3 ms/μm
conclusionThe combination of strong gradients and an expanded encoding model enables imaging of the prostate with unprecedented image quality. Replacing the commonly used EPI with spirals provides the inherent benefit of shorter echo times and superior readout efficiency and results in higher SNR, which is in particular relevant for considered applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.