ArticleBMC pulmonary medicine2024
Association between serum albumin and pulmonary function in adolescents: analyses of NHANES 2007-2012.
Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Maternal and perinatal nutritional programming of lung health and disease in childhood and early adulthood: Research gaps and opportunities-National Heart, Lung, and Blood Institute/National Institutes of Health Workshop Report.The Journal of allergy and clinical immunology · 2026Article
- Identification of Clinical Characteristics and Risk Factors of Invasive Pulmonary Aspergillosis in Patients with Acquired Immunodeficiency Syndrome: A Retrospective Study.Infection and drug resistance · 2026Article
- Reference intervals for serum albumin, total protein, and prealbumin in healthy children in Nanning, China.Biomarkers in medicine · 2025Article
- Association between neutrophil percentage-to-albumin ratio (NPAR) and sarcopenia in individuals with arthritis: a cross-sectional study.Frontiers in medicine · 2025Article
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7 authors.
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Abstract
backgroundPulmonary function tests (PFTs) are an important tool for assessing pulmonary diseases, although clinicians often find it challenging to accurately evaluate the pulmonary function of children.
methodsWe intend to investigate the association between serum albumin (SA) and lung function among U.S. adolescents. This cross-sectional study included 3,072 adolescents (aged 12 to 19) from 2007 to 2012National Health and Nutrition Examination Survey (NHANES). PFTs, including forced vital capacity (FVC)%predicted, forced expiratory volume in 1 s (FEV1)%predicted, FEV1/FVC%predicted, and maximum mid-expiratory flow (FEF25-75) % predicted, were utilized to assess the association between serum albumin levels and lung function. To explore the potential associations between SA and pulmonary function, we employed multivariate linear regression, subgroup analysis, smoothing curve fitting and threshold effect.
resultsA positive correlation was observed between serum albumin levels and pulmonary function. In the model with a fully adjusted, each 1 g/dL serum albumin increase in SA corresponded to an increase of 2.69% in FVC%pred, 5.8% in FEV1%pred, 10.99% in FEF25-75%pred and 2.98% in FEV1/FVC%pred. This association between SA and FEV1%pred differed across gender subgroups. A non-linear relationship was observed between SA and FEV1/FVC%pred.
conclusionOur results demonstrated a positive correlation between SA and lung function, suggesting a novel modality for evaluating pulmonary function, specifically in children. CLINICAL TRIAL NUMBER: Not applicable.
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