Evidence map›Paper›PMID 39496941›Full record

ReviewEuropean journal of clinical nutrition2025

Positive association of the thigh muscle thickness to intracellular-water ratio with handgrip strength, but not with the risk of mortality in hospitalized cancer patients: a longitudinal study.

Tatyanne L N Gomes, Jessica F M Ivo, Lara G Mainardi, Gustavo D Pimentel

Abstract readReview
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In one paragraph

Review in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatyanne L N GomesFaculty of Nutrition, Federal University of Goiás, Goiânia, Brazil.
Jessica F M IvoFaculty of Nutrition, Federal University of Goiás, Goiânia, Brazil.
Lara G MainardiFaculty of Nutrition, Federal University of Goiás, Goiânia, Brazil.
Gustavo D PimentelFaculty of Nutrition, Federal University of Goiás, Goiânia, Brazil. gupimentel@yahoo.com.br.ORCID http://orcid.org/0000-0002-2979-9819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the relationship between handgrip strength, muscle thickness, and the intracellular water ratio (MT/ICW) in cancer patients. It aimed to identify a cut-off point for the MT/ICW ratio that might influence survival. Conducted as an exploratory, longitudinal study in a public hospital, it included patients from 2018 to 2022, with follow-up until August 31, 2023. The cut-off for the MT/ICW ratio was determined based on its sensitivity for mortality. Results indicated that patients with an MT/ICW ratio >0.97 had significantly lower extracellular water percentages and greater muscle thickness. A positive association was found between the MT/ICW ratio and handgrip strength, even after adjusting for age, sex, extracellular water, and body mass index. However, patients with an MT/ICW ratio ≤0.97 showed no significant mortality risk. In conclusion, MT/ICW ratio >0.97 mm/L in hospitalized cancer patients was positively associated with handgrip strength, but not risk of mortality.

Indexed as

Body WaterHand StrengthMuscle, SkeletalNeoplasmsThighAgedFemaleHospitalizationHumansLongitudinal StudiesMaleMiddle Aged

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.