Evidence map›Paper›PMID 39496765›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Point-of-care lung ultrasound for continuous positive airway pressure discontinuation in preterm infants.

Faith Myers, Reedhi Dasani, Jacklin Tong, Shelby Vallandingham-Lee, Christine Manipon, Alex Dahlen, Daniele De Luca, Yogen Singh, Alexis S Davis, Valerie Y Chock and 1 more

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Faith MyersDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA. faith.myers@childrensMN.org.ORCID 0000-0002-5073-5465
Reedhi DasaniDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.ORCID 0000-0002-4077-0427
Jacklin TongLucile Packard Children's Hospital at Stanford University, Palo Alto, CA, USA.
Shelby Vallandingham-LeeLucile Packard Children's Hospital at Stanford University, Palo Alto, CA, USA.
Christine ManiponLucile Packard Children's Hospital at Stanford University, Palo Alto, CA, USA.
Alex DahlenBiostatistical Collaboration and Consultation Core, Department of Biostatistics, School of Global Public Health at New York University, New York, NY, USA.
Daniele De LucaDivision of Pediatrics and Neonatal Critical Care, South Paris University Hospitals, Medical Center "A. Beclere, " Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.ORCID 0000-0002-3846-4834
Yogen SinghDepartment of Pediatrics, Division of Neonatology, UC Davis Children's Hospital, Sacramento, CA, USA.ORCID 0000-0002-5207-9019
Alexis S DavisDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.ORCID 0000-0002-7862-8661
Valerie Y ChockDepartment of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA, USA.ORCID 0000-0002-6942-1423
Shazia BhombalDivision of Neonatology, Emory University/Children's Healthcare of Atlanta, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if the lung ultrasound score (LUS) is predictive of successful continuous positive airway pressure (CPAP) discontinuation in preterm neonates born <32 weeks' gestation with history of respiratory distress syndrome. STUDY

designRetrospective study of preterm infants requiring CPAP. Univariate and multivariate logistic regression performed to formulate a predictive score using clinical variables with and without LUS. Area under the curve (AUC) was compared to determine the added predictive ability of LUS.

resultsForty-one patients with discontinuation attempts associated with a LUS were included. Lower LUS obtained within 0-7 days prior to CPAP discontinuation was associated with successful CPAP discontinuation (OR 0.46 [0.23, 0.91]; p = 0.025). Cross-validated AUC for clinical variables alone (Model 1) was 0.85 (95% CI: 0.74-0.93) versus 0.90 (95% CI: 0.81-0.97) when LUS was incorporated (Model 2, p < 0.001). AUC of LUS alone was 0.83 (95% CI: 0.68-0.93, p < 0.0001).

conclusionsIn preterm infants requiring CPAP, LUS aids in the prediction of successful CPAP discontinuation and may significantly improve a predictive tool.

Indexed as

Continuous Positive Airway PressureInfant, PrematureLungRespiratory Distress Syndrome, NewbornUltrasonographyArea Under CurveFemaleGestational AgeHumansInfant, NewbornLogistic ModelsMaleMultivariate AnalysisPoint-of-Care SystemsPredictive Value of TestsRetrospective Studies

Identifiers

PMID39496765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.