Evidence map›Paper›PMID 39496448›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Radiation Nephropathy Complicated by Tubulointerstitial Nephritis with Predominantly Lymphocyte and Plasma Cell Infiltration.

Tatsuaki Kosaka, Koji Takaori, Azusa Izumiya, Daisuke Hirai, Mitsuteru Koizumi, Shinya Yamamoto, Akiko Mii, Akira Shimizu, Kiyonao Nakamura, Norio Araki and 1 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tatsuaki KosakaDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.
Koji TakaoriDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.
Azusa IzumiyaDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.
Daisuke HiraiDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.
Mitsuteru KoizumiDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.
Shinya YamamotoDepartment of Nephrology, Kyoto University Graduate School of Medicine, Japan.
Akiko MiiDepartment of Endocrinology, Metabolism and Nephrology, Nippon Medical School, Japan.
Akira ShimizuDepartment of Analytic Human Pathology, Nippon Medical School, Japan.
Kiyonao NakamuraDepartment of Radiation Oncology, Kyoto City Hospital, Japan.
Norio ArakiDepartments of Radiation Oncology, National Hospital Organization Kyoto Medical Center, Japan.
Koichi SetaDepartments of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 64-year-old Japanese woman presented with gross hematuria and was diagnosed with stage IVB cervical cancer. Renal dysfunction was observed following chemoradiation therapy, and a renal biopsy revealed renal thrombotic microangiopathy (TMA) and tubulointerstitial nephritis (TIN), which are atypical features of radiation nephropathy. Contrast-enhanced computed tomography revealed wedge-shaped areas of high contrast, consistent with areas of high radiation dose in the kidneys, thus leading to the diagnosis of radiation nephropathy. This case underscores the importance of integrating clinical, pathological, and radiological findings for the diagnosis of radiation nephropathy, atypical renal biopsy findings, and a combination of TIN and renal TMA.

Indexed as

LymphocytesNephritis, InterstitialPlasma CellsRadiation InjuriesFemaleHumansMiddle AgedThrombotic MicroangiopathiesUterine Cervical Neoplasmscontrast-enhanced computed tomographyradiation nephropathythrombotic microangiopathytubulointerstitial nephritis

Identifiers

PMID39496448
PMCPMC12222972

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.