Evidence map›Paper›PMID 39496239›Full record

ArticleAnnals of nutrition & metabolism2025

Impact of Nutritional Therapy during Intensive Care Unit Admission on Post-Intensive Care Syndrome in Patients with COVID-19.

Shinya Suganuma, Kensuke Nakamura, Hideaki Kato, Muneaki Hemmi, Keiichiro Kawabata, Mariko Hosozawa, Yoko Muto, Miyuki Hori, Arisa Iba, Tomohiro Asahi and 7 more

Abstract read
In one paragraph

Article in Annals of nutrition & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shinya SuganumaCritical Care Medicine, Yokohama City University Hospital, Yokohama, Japan, uz.831@icloud.com.
Kensuke NakamuraCritical Care Medicine, Yokohama City University Hospital, Yokohama, Japan.
Hideaki KatoInfection Prevention and Control, Yokohama City University Hospital, Yokohama, Japan.
Muneaki HemmiCritical Care Medicine, Yokohama City University Hospital, Yokohama, Japan.
Keiichiro KawabataCritical Care Medicine, Yokohama City University Hospital, Yokohama, Japan.
Mariko HosozawaInstitute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Yoko MutoInstitute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Miyuki HoriInstitute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Arisa IbaInstitute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Tomohiro AsahiCardiology, Naha City Hospital, Okinawa, Japan.
Akira KawauchiCritical Care and Emergency Medicine, Japanese Red Cross Maebashi Hospital, Maebashi, Japan.
Shigeki FujitaniEmergency Medicine and Critical Care Medicine, St. Marianna University, Kawasaki, Japan.
Junji HatakeyamaEmergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Taku OshimaEmergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Kohei OtaEmergency and Critical Care Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Hiroshi KamijoEmergency and Critical Care Medicine, Shinshu University School of Medicine, Nagano, Japan.
Hiroyasu IsoInstitute for Global Health Policy Research (iGHP), Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNutritional therapy is an important component of intensive care. We investigated the associations of nutritional therapy in the acute phase of severe COVID-19 with the long-term outcomes of post-intensive care syndrome (PICS) and post-COVID-19 conditions.

methodsA questionnaire on the health status after COVID-19 was sent to patients 1 year after infection and PICS was evaluated. Total energy and protein intakes during the first week after admission to the intensive care unit (ICU) were calculated. The primary endpoint was a decrease in quality of life (QOL) defined by EuroQol5-dimensions 5-level (EQ5D5L) <0.8. A multivariable regression analysis was used to examine.

resultsA total of 220 ICU patients were included in this study. Median total energy and protein intakes were 65.1 kcal/kg/week and 3.3 g/kg/week, respectively. Total energy and protein intakes were associated with EQ5D5L scores (energy: unit odds ratio 0.98 [0.97-0.99], p value <0.01; protein: unit odds ratio 0.72 [0.59-0.87], p value <0.01). Insufficient total energy and protein intakes were associated with malaise, arthralgia, myalgia, palpitations, sleep disturbance, and muscle weakness.

conclusionsPoor nutrition during the first week after ICU admission was associated with a decreased QOL 1 year after. These nutrition shortages were also associated with an increased risk of developing PICS, post-COVID-19 conditions, which may contribute to decreased QOL.

introductionNutritional therapy is an important component of intensive care. We investigated the associations of nutritional therapy in the acute phase of severe COVID-19 with the long-term outcomes of post-intensive care syndrome (PICS) and post-COVID-19 conditions.

methodsA questionnaire on the health status after COVID-19 was sent to patients 1 year after infection and PICS was evaluated. Total energy and protein intakes during the first week after admission to the intensive care unit (ICU) were calculated. The primary endpoint was a decrease in quality of life (QOL) defined by EuroQol5-dimensions 5-level (EQ5D5L) <0.8. A multivariable regression analysis was used to examine.

resultsA total of 220 ICU patients were included in this study. Median total energy and protein intakes were 65.1 kcal/kg/week and 3.3 g/kg/week, respectively. Total energy and protein intakes were associated with EQ5D5L scores (energy: unit odds ratio 0.98 [0.97-0.99], p value <0.01; protein: unit odds ratio 0.72 [0.59-0.87], p value <0.01). Insufficient total energy and protein intakes were associated with malaise, arthralgia, myalgia, palpitations, sleep disturbance, and muscle weakness.

conclusionsPoor nutrition during the first week after ICU admission was associated with a decreased QOL 1 year after. These nutrition shortages were also associated with an increased risk of developing PICS, post-COVID-19 conditions, which may contribute to decreased QOL.

Indexed as

COVID-19Critical CareNutrition TherapyAgedCritical IllnessDietary ProteinsEnergy IntakeFemaleHumansIntensive Care UnitsMaleMiddle AgedNutritional StatusQuality of LifeSARS-CoV-2Surveys and QuestionnairesDietary ProteinsCritical careNutritional therapyPost-COVID-19 conditionPost-intensive care syndrome

Identifiers

PMID39496239
PMCPMC11797927

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.