Evidence map›Paper›PMID 39496093›Full record

ArticleJournal of medicinal chemistry2024

Optimization of Antiproliferative Properties of Triimine Copper(II) Complexes.

Katarzyna Choroba, Bartosz Zowiślok, Sławomir Kula, Barbara Machura, Anna M Maroń, Karol Erfurt, Cristiana Marques, Sandra Cordeiro, Pedro V Baptista, Alexandra R Fernandes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katarzyna ChorobaInstitute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.ORCID 0000-0003-0168-5753
Bartosz ZowiślokInstitute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
Sławomir KulaInstitute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.ORCID 0000-0003-4520-1570
Barbara MachuraInstitute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
Anna M MarońInstitute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.ORCID 0000-0001-8245-5532
Karol ErfurtDepartment of Chemical Organic Technology and Petrochemistry, Silesian University of Technology, Krzywoustego 4, 44-100 Gliwice, Poland.
Cristiana MarquesAssociate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.
Sandra CordeiroAssociate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.
Pedro V BaptistaAssociate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0001-5255-7095
Alexandra R FernandesAssociate Laboratory i4HB - Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.ORCID 0000-0003-2054-4438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cu(II) complexes with 2,2':6',2″-terpyridines (terpy) and 2,6-bis(thiazol-2-yl)pyridines (dtpy) with 1- or 2-naphtyl and methoxy-naphtyl were synthesized to elucidate the impact of the triimine core, naphtyl linking mode, and presence of methoxy groups on the antiproliferative activity of [CuCl

Indexed as

Antineoplastic AgentsCell ProliferationCoordination ComplexesCopperReactive Oxygen SpeciesAnimalsApoptosisCell Line, TumorChick EmbryoDoxorubicinDrug Screening Assays, AntitumorHCT116 CellsHumansIminesPyridinesStructure-Activity RelationshipAntineoplastic AgentsCoordination ComplexesCopperDoxorubicinIminesPyridinesReactive Oxygen Species

Identifiers

PMID39496093
PMCPMC11571215

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.