Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
15 authors.
Lucas G Miller *McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.ORCID 0009-0008-0575-6030
Wantae Kim *McKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.
Shawn Schowe *Department of Chemistry, University of Colorado Denver, Denver, CO 80217.
Kathleen TaylorMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-9731-0704
Runhua HanMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.ORCID 0000-0001-7834-6800
Vashita JainDepartment of Chemistry, University of Colorado Denver, Denver, CO 80217.
Raeyeon ParkArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843.
Mark ShermanMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-8940-6212
Janssen FangDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
Haydee RamirezDepartment of Chemistry, University of Colorado Denver, Denver, CO 80217.ORCID 0000-0003-0377-4151
Andrew EllingtonDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.
Phanourios TamamisArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843.
Marino J E ResendizDepartment of Chemistry, University of Colorado Denver, Denver, CO 80217.ORCID 0000-0001-5631-2722
Y Jessie ZhangDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-9360-5388
Lydia ContrerasMcKetta Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712.ORCID 0000-0001-5010-5511
Funding
Deciphering the phosphorylation pattern of RNA polymerase II for eukaryotic transcriptionR35GM148356 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yan Jessie Zhang · 2023 to 2026
$2.3M
Novel mechanisms of posttranscriptional regulation by CsrAR01GM135495 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI CONTRERAS, LYDIA MARIA · 2020 to 2024
$1.8M
Establishing the impact of 8-Oxo-7,8-dihydroguanosine (8-oxoG) on the structure and function of RNA. Part IIIR15GM132816 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Marino JE Resendiz, Haobin Wang · 2019 to 2026
$1.4M
Directed evolution of broadly fungible biosensorsR01GM146093 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Andrew D Ellington · 2023 to 2026
$1.3M
RNA-mediated regulation of antioxidant accumulation during recovery from radiation stressR21ES025923 · NIEHS · UNIVERSITY OF TEXAS AT AUSTIN · PI CONTRERAS, LYDIA MARIA · 2017 to 2018
$417k
Camille and Henry Dreyfus Foundation (Dreyfus Foundation) TH-21-028DOD | USAF | AMC | Air Force Office of Scientific Research (AFOSR) FA9550-20-1-0131HHS | National Institutes of Health (NIH) 1R01GM146093-01A1HHS | National Institutes of Health (NIH) 5R01GM135495-02HHS | National Institutes of Health (NIH) 5R21ES025923-02HHS | National Institutes of Health (NIH) R35GM148356HHS | NIH | National Institute of General Medical Sciences (NIGMS) 2R15GM132816-02National Science Foundation (NSF) 2022146National Science Foundation (NSF) 2218477National Science Foundation (NSF) MRI-2117934NIEHS NIH HHS R21 ES025923NIGMS NIH HHS R01 GM135495NIGMS NIH HHS R01 GM146093NIGMS NIH HHS R15 GM132816NIGMS NIH HHS R35 GM148356NSF | National Science Foundation Graduate Research Fellowship Program (GRFP) DGE-1610403Office of the Vice President for Research at Colorado State University SCR_021758The Welch Foundation F-1654The Welch Foundation F-1756
6 · The paper itself
Abstract
RNA oxidation, predominantly through the accumulation of 8-oxo-7,8-dihydroguanosine (8-oxo-rG), represents an important biomarker for cellular oxidative stress. Polynucleotide phosphorylase (PNPase) is a 3'-5' exoribonuclease that has been shown to preferentially recognize 8-oxo-rG-containing RNA and protect
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Selective 8-oxo-rG stalling occurs in the catalytic core of polynucleotide phosphorylase (PNPase) during degradation. · full record | OpenQuestion