Evidence map›Paper›PMID 39495920›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Combatting melioidosis with chemical synthetic lethality.

Yifan Zhang, Kirklin L McWhorter, Paul C Rosen, Jennifer R Klaus, Étienne Gallant, Cindy Y Amaya Lopez, Riddhi Jhunjhunwala, Josephine R Chandler, Katherine M Davis, Mohammad R Seyedsayamdost

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Infection and drug resistance · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yifan ZhangDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.ORCID 0000-0001-6419-5108
Kirklin L McWhorterDepartment of Chemistry, Emory University, Atlanta, GA 30033.
Paul C RosenDepartment of Chemistry, Princeton University, Princeton, NJ 08544.ORCID 0000-0001-7414-454X
Jennifer R KlausDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.
Étienne GallantDepartment of Chemistry, Princeton University, Princeton, NJ 08544.
Cindy Y Amaya LopezDepartment of Chemistry, Emory University, Atlanta, GA 30033.ORCID 0000-0002-5419-0458
Riddhi JhunjhunwalaDepartment of Chemistry, Emory University, Atlanta, GA 30033.
Josephine R ChandlerDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS 66045.ORCID 0000-0001-8944-9813
Katherine M DavisDepartment of Chemistry, Emory University, Atlanta, GA 30033.ORCID 0000-0002-0258-8907
Mohammad R SeyedsayamdostDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544.ORCID 0000-0003-2707-4854

Funding

User Training & OutreachP30GM138396 · NIGMS · UCHICAGO ARGONNE, LLC · PI JANET L. SMITH · 2020 to 2026
$34.3M
Quorum sensing evolution and function in mixed bacterial communitiesR35GM133572 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI CHANDLER, JOSEPHINE R · 2019 to 2024
$2.1M
High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APSS10OD012289 · OD · UNIVERSITY OF CHICAGO · PI FISCHETTI, ROBERT F. · 2014 to 2014
$2.0M
Unraveling the dynamics that enable unusual heme enzyme reactivityR35GM147557 · NIGMS · EMORY UNIVERSITY · PI Katherine Marie Davis · 2022 to 2026
$1.9M
Exploring a New Dimension of Microbial Secondary MetabolismR01GM140034 · NIGMS · PRINCETON UNIVERSITY · PI SEYEDSAYAMDOST, MOHAMMAD R · 2021 to 2024
$1.2M
NIGMS NIH HHS P30 GM138396NIGMS NIH HHS R01 GM140034NIGMS NIH HHS R35 GM133572NIGMS NIH HHS R35 GM147557NIH HHS S10 OD012289
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BurkholderiaMelioidosisTrimethoprimAnti-Bacterial AgentsBacterial ProteinsBurkholderia pseudomalleiHumansAnti-Bacterial AgentsBacterial ProteinsTrimethoprimantibioticsBurkholderia thailandensisfolate biosynthesisFolE2natural products

Identifiers

PMID39495920
PMCPMC11573665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.