Evidence map›Paper›PMID 39495918›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Identification and characterization of the lipoprotein

Krista M Armbruster, Jiawen Jiang, Mariana G Sartorio, Nichollas E Scott, Jenna M Peterson, Jonathan Z Sexton, Mario F Feldman, Nicole M Koropatkin

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Article
  7. Identification and characterization of the functional LolB ortholog inbioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. LipoproteinmBio · 2025
    Article
  11. Structural and functional analysis of theFrontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Krista M ArmbrusterDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.
Jiawen JiangDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.ORCID 0000-0002-5449-2632
Mariana G SartorioDepartment of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110.ORCID 0000-0001-5539-2388
Nichollas E ScottDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, VIC 3000, Australia.ORCID 0000-0003-2556-8316
Jenna M PetersonDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.
Jonathan Z SextonDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109.
Mario F FeldmanDepartment of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110.
Nicole M KoropatkinDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.ORCID 0000-0002-2459-3336

Funding

Unraveling the enzymatic pathway of gut bacterial mucus degradation to treat inflammationR01DK125445 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOROPATKIN, NICOLE M, MARTENS, ERIC C · 2020 to 2023
$2.2M
Laser-based high content imaging microscopeS10OD034245 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEXTON, JONATHAN ZACHARY · 2024 to 2024
$1.4M
Outer Membrane Vesicles in Human Gut BacteriaR21AI151873 · NIAID · WASHINGTON UNIVERSITY · PI FELDMAN, MARIO · 2020 to 2021
$433k
Biogenesis and functions of outer membrane vesicles in BacteroidetesR21AI168719 · NIAID · WASHINGTON UNIVERSITY · PI FELDMAN, MARIO · 2022 to 2023
$432k
Bacteroides use a novel N-acyltransferase for lipoprotein synthesis and survivalR21AI180287 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOROPATKIN, NICOLE M · 2024 to 2025
$413k
Department of Education and Training | Australian Research Council (ARC) DP210100362Department of Education and Training | Australian Research Council (ARC) FT200100270HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK125445HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases (DMID) R21AI151873HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases (DMID) R21AI168719Michigan Life Sciences Fellows Program N/ANIAID NIH HHS R21 AI151873NIAID NIH HHS R21 AI168719NIAID NIH HHS R21 AI180287NIDDK NIH HHS R01 DK125445NIH HHS S10 OD034245
6 · The paper itself

Abstract

Members of the Bacteroidota compose a large portion of the human gut microbiota, contributing to overall gut health via the degradation of various polysaccharides. This process is facilitated by lipoproteins, globular proteins anchored to the cell surface by a lipidated N-terminal cysteine. Despite their importance, lipoprotein synthesis by these bacteria is understudied. In

Indexed as

AcyltransferasesBacteroidesLipoproteinsBacterial ProteinsEscherichia coliHumansAcyltransferasesBacterial ProteinsLipoproteinsacyltransferaseBacteroidescell surfacelipoproteins

Identifiers

PMID39495918
PMCPMC11573676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.