Evidence map›Paper›PMID 39495866›Full record

ArticleAnalytical chemistry2024

Enhancing SARS-CoV-2 Lineage Surveillance through the Integration of a Simple and Direct qPCR-Based Protocol Adaptation with Established Machine Learning Algorithms.

Cleber Furtado Aksenen, Debora Maria Almeida Ferreira, Pedro Miguel Carneiro Jeronimo, Thais de Oliveira Costa, Ticiane Cavalcante de Souza, Bruna Maria Nepomuceno Sousa Lino, Allysson Allan de Farias, Fabio Miyajima

Abstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. COVID-19: Lessons Learned from Molecular and Clinical Research.International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cleber Furtado AksenenDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.ORCID 0000-0002-5297-7505
Debora Maria Almeida FerreiraDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Pedro Miguel Carneiro JeronimoDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Thais de Oliveira CostaDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Ticiane Cavalcante de SouzaDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Bruna Maria Nepomuceno Sousa LinoDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Allysson Allan de FariasDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.
Fabio MiyajimaDepartment of Biotechnology, Oswaldo Cruz Foundation, Eusébio 61773-270, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging and evolving Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) lineages, adapted to changing epidemiological conditions, present unprecedented challenges to global public health systems. Here, we introduce an adapted analytical approach that complements genomic sequencing, applying a cost-effective quantitative polymerase chain reaction (qPCR)-based assay. Viral RNA samples from SARS-CoV-2 positive cases detected by diagnostic laboratories or public health network units in Ceará, Brazil, were tracked for genomic surveillance and analyzed by using paired-end sequencing combined with integrative genomic analysis. Validation of a key structural variation was conducted with gel electrophoresis for the presence of a specific

Indexed as

COVID-19Machine LearningRNA, ViralSARS-CoV-2HumansReal-Time Polymerase Chain ReactionRNA, Viral

Identifiers

PMID39495866
PMCPMC11579975

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.