Evidence map›Paper›PMID 39495758›Full record

ArticlePloS one2024

Prevalence of lymphopenia in the American population: Insights from demographic, BMI, and lifestyle factors.

Wenchi Xie, Landie Ji, Landan Kang, Qian Li, Dan Luo, Qingquan He, Jie Mei

Erratum issuedAbstract read
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Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Wenchi XieCollege of Clinical Medicine, Southwest Medical University, Luzhou, Sichuan, China.ORCID 0009-0007-1180-6607
Landie JiCollege of Clinical Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Landan KangCollege of Clinical Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Qian LiCollege of Clinical Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Dan LuoCollege of Clinical Medicine, Southwest Medical University, Luzhou, Sichuan, China.
Qingquan HeCollege of Clinical Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Jie MeiDepartment of Obstetrics and Gynaecology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID 0009-0006-6381-6754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the difference in the prevalence of lymphopenia in the American population according to demographic characteristics, body mass index (BMI) and living habits.

methodsA total of 33,365 participants aged over 1 were included in the 2009-2018 National Health and Nutrition Survey (NHANES). All analyses used weighted samples and considered the layering and clustering of the design.

resultsUsing white participants as a reference, the prevalence of lymphopenia in Mexican-American participants was significantly lower than that of white participants (P = 0.018). There was no significant difference in the prevalence of lymphopenia between black participants (P = 0.376) and white participants. The prevalence of lymphopenia was 1.81% (95%CI, 1.53%-2.10%) for white participants, 1.08% (95%CI, 0.78%-1.39%) for black participants, and 0.42% (95%CI, 0.17%-0.68%) for Mexican-American participants. The prevalence of lymphopenia increases with age, reaching a peak of 6.84% among elderly participants aged 75 and above. In terms of the gender difference, the prevalence of lymphopenia in men is significantly higher than that in women (P<0.001). Individuals who smoke (P<0.001), consume alcohol (P = 0.032), engage in regular exercise (P = 0.031), have sleep disorders (P<0.001) and those classified as having an unhealthy weight (P<0.001) had a higher average lymphocyte count. The prevalence of lymphopenia in participants with sleep disorders is significantly higher than those without sleep disorders (P = 0.014). However, no significant differences were observed among the classification variables of smoking, drinking, exercise, and BMI.

conclusionIn the diagnosis and treatment of lymphopenia, clinicians should consider the influence of factors such as race, gender, age, sleep disorders, and other unhealthy lifestyle habits to improve the accuracy of diagnosis and treatment, thereby reducing the high mortality risk associated with lymphopenia. Consequently, we propose a novel perspective that the diagnosis and treatment of lymphopenia should be tailored to the lymphocyte levels of specific subpopulations, rather than applying a generalized approach.

Indexed as

Body Mass IndexLife StyleLymphopeniaAdolescentAdultAgedBlack or African AmericanChildChild, PreschoolFemaleHumansInfantMaleMexican AmericansMiddle AgedNutrition Surveys

Identifiers

PMID39495758
PMCPMC11534243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.