Evidence map›Paper›PMID 39495468›Full record

ArticlePain and therapy2025

Transforaminal Endoscopic Lumbar Discectomy versus Coblation Nucleoplasty Combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondylolisthesis.

Yuyu Guo, Liuhu Han, Tingting Li, Bingbing Xu, Penghui Ke, Jun Hu, Rongyi Zhang, Yan Guo, Long Zhao, Likui Wang

Abstract read
In one paragraph

Article in Pain and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuyu Guo *Department of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Liuhu Han *Department of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Tingting Li *Department of Anesthesiology, AnHui No. 2 Provincial People's Hospital, HeFei, China.
Bingbing XuDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Penghui KeDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Jun HuDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Rongyi ZhangDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Yan GuoDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Long ZhaoDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China.
Likui WangDepartment of Pain Medicine, The First Affiliated Hospital of AnHui Medical University, HeFei, China. wlk9560@163.com.

Funding

Research Foundation of Anhui Academy of Translational Medicine 2023zhyx-C45
6 · The paper itself

Abstract

introductionTo investigate the short-term clinical effect of transforaminal endoscopic lumbar discectomy (TELD) versus coblation nucleoplasty (CN) combined with collagenase chemonucleolysis (CCNL) in the treatment of lumbar disc herniation (LDH) with grade I degenerative spondylolisthesis.

methodsFrom January 2019 to December 2020, 60 patients who had LDH with grade I degenerative spondylolisthesis were divided into two groups. Group A adopted TELD while Group B adopted CN combined with CCNL. The surgical efficacy was evaluated according to the visual analogue scale (VAS), oswestry disability index (ODI), quality of recovery-15 (QoR-15), and modified MacNab criteria. Imaging findings including lumbar lordosis (LL), segmental lordosis angle (SL), slip percentage (SP), and disc height (DH) were compared between the two groups pre-operation and at the last follow-up.

resultsVAS (back and leg), ODI, and QoR-15 were significantly decreased at each time point after operation in all groups. There were significant differences in VAS (back and leg), ODI, and QoR-15 between the two groups at 3 days post-operation (P < 0.05), VAS (leg), ODI, and QoR-15 at 3 months post-operative (P < 0.05), and QoR-15 at 6 months post-operative (P < 0.05). There was no significant difference in LL, SL, SP, and DH between the two groups at the last follow-up (P > 0.05).

conclusionBoth the two operations can relieve the symptoms of lower back and leg pain in patients, and neither of the two operations caused further progress of lumbar spondylolisthesis. Compared with CN combined with CCNL, TELD had more significant improvement in early lower back and leg pain and shorter post-operative duration of hospitalization.

trial registrationThe trial was registered on ClinicalTrials.gov (ChiCTR2300076809).

Indexed as

Coblation nucleoplastyCollagenase chemonucleolysisLumbar disc herniationPainTransforaminal endoscopic lumbar discectomy

Identifiers

PMID39495468
PMCPMC11751196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.