Evidence map›Paper›PMID 39495455›Full record

ArticleJournal of general internal medicine2025

Disparities in Colorectal Cancer Screening Before and After the Onset of the COVID Pandemic.

Sunny Siddique, Rong Wang, Jacquelyne J Gaddy, Jessica M Stempel, Joshua L Warren, Cary P Gross, Xiaomei Ma

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Sunny SiddiqueDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, USA. sunny.siddique@yale.edu.ORCID 0000-0002-5746-1161
Rong WangDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, USA.
Jacquelyne J GaddyCancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, USA.
Jessica M StempelDepartment of Medicine (Hematology/Oncology), Yale School of Medicine, New Haven, USA.
Joshua L WarrenDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Cary P GrossCancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, USA.
Xiaomei MaDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Yale Cancer Prevention and Control Training ProgramT32CA250803 · NCI · YALE UNIVERSITY · PI Melinda L Irwin, Xiaomei Ma · 2020 to 2026
$2.3M
Examining Early Life Risk Factors and Patterns of Screening for Early-Onset Colorectal CancerF31CA281335 · NCI · YALE UNIVERSITY · PI SIDDIQUE, ARFAN · 2023 to 2024
$88k
NCATS NIH HHS UL1 TR001863NCI NIH HHS F31 CA281335NCI NIH HHS T32 CA250803NIH HHS 1F31CA281335-01
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) screening is underutilized among those with lower socioeconomic status and in racial and ethnic minoritized populations who have been disproportionately impacted by COVID.

objectiveTo compare disparities in CRC screening before and after the onset of the COVID pandemic among privately insured individuals.

designRetrospective cohort study using deidentified claims data from the USA between January 1, 2017, and December 31, 2022.

participantsBlue Cross Blue Shield beneficiaries aged 50-75 years with average risk of CRC. MAIN MEASURE(S): Mean screening use was compared by demographic and area-level socioeconomic factors between the periods preceding (January 1, 2017 to February 28, 2020) and following (July 1, 2020 to December 31, 2022) the onset of the COVID pandemic. Difference-in-differences analysis was used to evaluate changes in screening differences.

resultsOur study included 21,724,223 beneficiaries. Compared to males, females had higher screening in both periods (p < 0.05), and this sex difference in screening increased 1.63% (95% confidence interval [CI]: 1.32%, 1.94%) following the onset of the pandemic. Compared to residents in areas with high socioeconomic status (SES), low SES area residents had lower screening (p < 0.001) during both periods. Furthermore, this difference grew 4.32% (95% CI, 3.76%, 4.88%) during the post-onset period. Metropolitan area residents had higher screening than non-metropolitan area residents during both periods (p < 0.001); however, this difference decreased 0.77% (95% CI, 0.34%, 1.20%) during the post-onset period. Among beneficiaries with high risk of CRC, the difference in screening based on social deprivation index and metropolitan area status increased 6.99% (95% CI, 5.77%, 8.20%) and 1.82% (95% CI, 0.88%, 2.74%), respectively.

conclusionsAmong privately insured individuals, CRC screening after the COVID pandemic recovered unevenly based on sex, area-level socioeconomic measures, and metropolitan area status, with pre-pandemic disparities persisting and even worsening for some of the factors.

Indexed as

Colorectal NeoplasmsCOVID-19Early Detection of CancerHealthcare DisparitiesAgedCohort StudiesFemaleHumansMaleMiddle AgedPandemicsRetrospective StudiesSocioeconomic FactorsUnited Statescolorectal cancer screeningCOVIDdisparity

Identifiers

PMID39495455
PMCPMC11861447

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.