Evidence map›Paper›PMID 39495322›Full record

ReviewFunctional & integrative genomics2024

CRISPR/Cas technology: fueling the future of Biofuel production with sugarcane.

A Ghane, P K Malhotra, G S Sanghera, S K Verma, N S Jamwal, L Kashyap, S H Wani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Functional & integrative genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A GhaneSchool of Agricultural Biotechnology, PAU, Ludhiana, India.
P K MalhotraSchool of Agricultural Biotechnology, PAU, Ludhiana, India. pkmalhotra-soab@pau.edu.
G S SangheraRegional., Research Station, Punjab Agricultural University, Kapurthala, India.
S K VermaInstitute of Biological Science, SAGE University, Indore, India.
N S JamwalRegional., Research Station, Punjab Agricultural University, Kapurthala, India.
L KashyapDepartment of Plant Breeding and Genetics, PAU, Ludhiana, India.
S H WaniMountain Research Center for Field Crop, SKUAST Srinagar, Jammu and Kashmir, Khudwani, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of present review is to provide a scientific overview of sugarcane as a potential feedstock for biofuel and use of genome editing approach for improvement of industrial and agronomical traits in sugarcane. Sugarcane, a perennial tropical grass with a high biomass index, is a promising feedstock for bioethanol production, and its bagasse, rich in lignocellulosic material, serves as an ideal feedstock for producing second-generation bioethanol. To improve the conversion of sugarcane biomass into biofuels, developing varieties with improved biomass degradability and high biomass and sucrose content is essential. The complex genome architecture and earlier lack of sequence data hindered biotechnological advancements in sugarcane, but recent genome sequence updates offer new opportunities for sugarcane improvement. The first genetically modified sugarcane was developed in 1992 by Bower and Birch using microprojectile bombardment of embryogenic callus. Since then, transgenic techniques have rapidly evolved, leading to the advancement of genome editing technologies. Application of genome editing tools particularly CRISPR/Cas system has been successfully used in sugarcane for editing. Recently, multiple alleles of the magnesium chelatase and acetolactate synthase genes in sugarcane have been successfully edited through multiplexing. Additionally, CRISPR-edited sugarcane varieties with modified cell wall components and increased sucrose content for enhanced bioethanol production have been developed. At the end, the future of CRISPR-edited crops will depend on how well regulatory frameworks adapt to the rapidly evolving technology.

Indexed as

BiofuelsCRISPR-Cas SystemsGene EditingSaccharumBiomassGenome, PlantPlants, Genetically ModifiedBiofuelsBiofuelCRISPR/CasGenome editingLignocellulosic biomassSugarcane

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.