Evidence map›Paper›PMID 39495274›Full record

ArticleSurgical and radiologic anatomy : SRA2024

Fiber anatomy and histological characteristics of the innervation of the triangular fibrocartilage complex.

Tonglong Xu, Xiaoyun Pan, Jingyi Mi

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Article in Surgical and radiologic anatomy : SRA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Tonglong XuMedical College, Soochow University, Suzhou, China.
Xiaoyun PanWuxi 9th People's Hospital Affiliated to Soochow University, Liangxi Road, No.999, Binhu District, Wuxi, Jiangsu, China.
Jingyi MiMedical College, Soochow University, Suzhou, China. mijingyi@suda.edu.cn.

Funding

the Major scientific research project of Wuxi Municipal Health Commission Z202108the Shanghai Key Laboratory of Peripheral Nerve and Microsurgery 20DZ2270200
6 · The paper itself

Abstract

purposeTo evaluate the precise origin of sensory nerves through gross anatomical study of the TFCC, synthesized alongside imaging and histological techniques.

methodSix cadaveric forearm specimens were obtained to map the course and branches of the ulnar nerve through macrodissection. Immunohistochemical staining targeting PGP 9.5 and type IV collagen was performed on frozen TFCC sections to visualize nerve fibers microscopically. Computed tomography, magnetic resonance imaging, and arthrography findings were also reviewed.

resultsAt the macroscopic level, the articular branches supplying the TFCC originated predominantly from the dorsal branch of the ulnar nerve. Microscopic analysis revealed positive PGP 9.5 expression and discernible neural marker expression, signifying fine nerve fiber ingrowth within the TFCC. Imaging modalities aided the diagnosis of TFCC lesions. The dorsal cutaneous branch of the ulnar nerve, medial cutaneous nerve of the forearm, and volar sensory branch of the ulnar nerve emerged as the principal nerves innervating the TFCC.

conclusionsThis study provides anatomical evidence that the TFCC receives innervation from branches of the ulnar nerve and contains sensory nerve fibers. These findings enhance understanding of potential neuropathic pain mechanisms in TFCC injuries and offer insights to guide surgical interventions. Further investigations are warranted to elucidate the clinical implications.

Indexed as

CadaverTriangular FibrocartilageUlnar NerveAgedAged, 80 and overArthrographyCollagen Type IVFemaleForearmHumansImmunohistochemistryMagnetic Resonance ImagingMaleMiddle AgedNerve FibersTomography, X-Ray ComputedCollagen Type IVUbiquitin ThiolesteraseUCHL1 protein, humanCadaveric researchSensory nervesThe triangular fibrocartilage complex

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.